University of Wisconsin-Madison Vision Research Training Program

项目摘要/摘要 技术进步正在推动基础设施不同领域的重大进步 研究。然而，这样的进步往往超过了它们的临床翻译。愿景社区 也不能幸免于这一困境。解决这一差距需要跨学科的方法来 在科学家和临床医生的协作环境中培训视力科学家，最终将 先进的医疗保健。我们正在重新提交视力研究培训计划(VRTP)T32 以帮助实现这一目标。VRTP是一项跨学科的培训计划， 跨越传统院系和学院界限的视觉科学。的目标是 该计划旨在提供与视觉研究相关的基础科学学科的研究培训。 VRTP还支持跨学科、协作和翻译研究，以便 学员准备进入新兴的互动研究环境并参与竞争。 目前，威斯康星大学麦迪逊分校没有与愿景相关的T32赠款或同等的支持机制。 事实上，视觉研究方面的任何培训现在都是以付费的方式与受训者进行的 由个别教员指导，不提供更广泛的背景和交叉协作 来自多个学科的教职员工。如果得到资助，VRTP将提供非凡的科学 培训以及提供与翻译和基础科学家互动的结构，以 达到我们规定的了解、预防和治疗视觉系统疾病的目标。 VRTP将作为校园VISION社区的焦点，实现这些目标 研究和社会目标。 威斯康星大学麦迪逊分校是培养未来视觉科学家和 提供博士后和博士后培训的基本要素。其中包括一个部门 眼科学和视觉科学(DOVS)在研究和研究方面同样具有典范能力 临床活动；麦克弗森眼科研究所(MERI)；医学院 公共卫生(SMPH)拥有著名的教师和物理设施；同样著名的毕业生 学校和学院包含众多的研究生课程和优秀的 生物、工程和计算科学方面的研究导师；以及 教职员工之间的合作和合作研究，使学生能够发展成为 杰出的翻译调查员。 目前，隶属于DOVS和MERI的16名教职员工组成了VRTP。他们是 根据四个研究重点领域进行组织：(A)发展和疾病 前段，(B)后段的发育和疾病；(C)眼 流行病学和遗传学；(D)高级视觉处理。正在请求支持 2名博士后实习生和2名博士后实习生。博士前实习生将得到 培训补助金为2-3年，博士后学员为1-3年。额外的年限 将通过几个来源获得支持，包括顾问的联邦和非 联邦资助、个人NRSA拨款以及SMPH和研究生院资源。培训 将由教学和研究两部分组成。学员将受益于个人 发展计划以及职业规划和咨询。重要的机构 除了招聘外，对培训的承诺将有助于确保该计划的成功 和保留计划，以增强多样性和指导负责任的行为的计划 研究。

PROJECT SUMMARY/ABSTRACT Technological advances are contributing to significant progress in different areas of basic research. However, such advances often exceed their clinical translation. The vision community is not exempt from this dilemma. Resolution of the gap requires an interdisciplinary approach to training vision scientists in a collaborative setting of scientists and clinicians that will ultimately advance medical care. We are re-submitting a Vision Research Training Program (VRTP) T32 grant to help achieve this objective. The VRTP is an interdisciplinary training program in the visual sciences that crosses traditional department and institute boundaries. The goal of the program is to provide research training in basic science disciplines relevant to vision research. The VRTP also supports interdisciplinary, collaborative and translational research so that trainees are prepared to enter and compete within emerging, interactive research environments. Currently, there is no vision-related T32 grant or equivalent support mechanism at UW-Madison. In fact, any training in vision research is now conducted in a disbursed fashion with trainees mentored by individual faculty and not provided a broader context and cross collaboration among faculty from multiple disciplines. If funded, the VRTP will provide exceptional scientific training as well as provide a structure for interactions with translational and basic scientists to meet our stated goal of understanding, preventing and treating diseases of the visual system. VRTP will act as a focal point for the vision community on campus in accomplishing these research and societal objectives. UW-Madison is an outstanding environment for the training of future vision scientists and provides the essential elements for pre- and post-doctoral training. These include a Department of Ophthalmology and Visual Sciences (DOVS) with equal exemplary prowess in research and clinical activities; the McPherson Eye Research Institute (MERI); a School of Medicine and Public Health (SMPH) with renown faculty and physical facilities; an equally renown Graduate School with Schools and Colleges containing numerous graduate programs and outstanding research mentors in the biological, engineering, and computational sciences; and a history of collegiality and collaborative research among faculty that allows students to develop into outstanding translational investigators. Sixteen faculty affiliated with DOVS and MERI currently comprise the VRTP. They are organized according to four areas of research emphasis: (a) Development and Diseases of the Anterior Segment, (b) Development and Diseases of the Posterior Segment; (c) Ocular Epidemiology and Genetics; (d) Higher Order Visual Processing. Support is being requested for 2 pre-doctoral trainees and 2 post-doctoral trainees. Pre-doctoral trainees will be supported by the training grant for 2-3 years and post-doctoral trainees for 1-3 years. Additional years of support will be obtained through several sources, including the Advisor's federal and non- federal funding, individual NRSA grants and SMPH and Graduate School resources. Training will consist of didactic and research components. Trainees will benefit from individual development plans as well as career planning and counseling. Significant institutional commitment to training will help ensure the success of the program, in addition to recruitment and retention plans to enhance diversity and plans for instruction in the responsible conduct of research.