Clinical Trials Network: Long Island Regional Node

描述（由申请人提供）：CTN的长岛节点成立于2000年，是首席研究员及其同事与曼哈顿，皇后区和长岛的几个社区治疗项目长期合作的种子。我们的目标是通过合作开展严格的多地点临床试验，测试药物依赖新治疗方法的有效性，并通过社区治疗提供者网络促进传播和采用发现有效的治疗方法，从而为CTN的基础工作作出贡献。我们的愿景包括促进基于双向原则的循证实践文化，使研究人员和社区临床医生在临床研究事业中被视为平等的合作者。在初始资助期内，长岛节点成员：1)为9个CTN临床试验提供了性能场地，并参与了2个已完成的调查研究；2)领导了2个CTN国家临床试验，目前已完成并在数据分析中；3)参与和/或获得14项辅助或平台研究的资助；4)担任艾滋病工作组、共同评估单元工作组、培训小组委员会、数据管理小组委员会、传播小组委员会、研究利用委员会、二次分析工作组主席，以及业务小组委员会、执行委员会和许多其他委员会、兴趣和工作组的成员；5)联合主持第二届调合年会（2002年），撰写或合作撰写论文26篇、专著1本，在专业会议上进行专题讨论会、演讲和培训60余次；6)发起和促进丁丙诺啡、激励性访谈和激励性激励的培训和传播工作。这项申请要求再提供3年的资金，以继续在最初供资期间开始的正在进行的活动，并在地方和全国开展新的研究和传播活动。我们将完成目前正在进行或启动的3个CTN试验（CTN-0028, CTN-0029, CTN-0030）的站点参与，继续发表我们领导的两项研究（CTN- 0015, CTN-0019）的结果和传播工作，为新的CTN试验提供站点，参与新的艾滋病毒筛查方案和其他新方案的方案开发团队，并继续在国家和地方层面的领导，培训和传播工作。我们还将继续鼓励并寻求外部资金支持在CTN平台上进行的研究。

DESCRIPTION (provided by applicant): The Long Island Node of the CTN was established in 2000 out of the seeds of long-standing collaborations between the Principal Investigator and his colleagues with several community-based treatment programs in Manhattan, Queens and Long Island. Our goals are to contribute to the fundamental work of the CTN by collaborating in the conduct of rigorous multi-site clinical trials testing the effectiveness of new treatments for drug dependence and promoting the dissemination and adoption of treatments found to be effective, through a network of community-based treatment providers. Our vision includes promoting the culture of evidence- based practice based on principles of bi-directionality such that both researchers and community-based clinicians are considered equal collaborators in the clinical research enterprise. Over the initial funding period, members of the Long Island Node have: 1) Provided performance sites for 9 CTN clinical trials, and participated in two completed survey studies, 2) Led two CTN national clinical trials, now completed and in data analysis; 3) Participated and/or obtained funding for 14 ancillary or platform studies; 4) Assumed national leadership as Chair of the HIV Workgroup, the Common Assessment Battery Workgroup, the Training Subcommittee, the Data Management Subcommittee, the Dissemination Subcommittee, the Research Utilization Committee, the Task Force on Secondary Analysis, as well as memberships on the Operations Subcommittee, the Executive Committee, and numerous other committees, interest and work groups; 5) Co-Chaired the second annual Blending Conference (2002), authored or coauthored 26 papers and one book, and delivered over 60 symposia, presentations and trainings at professional meetings; and 6) Initiated and fostered training and dissemination efforts in Buprenorphine, Motivational Interviewing and Motivational Incentives. This application requests funding for 3 additional years to continue the ongoing activities begun during the initial funding period and to develop new research and dissemination initiatives both locally and nationally. We will complete participation of sites in 3 CTN trials currently active or in start-up (CTN-0028, CTN-0029, CTN-0030), continue publication of results and dissemination efforts for the two studies we have led (CTN- 0015, CTN-0019), contribute sites to new CTN trials, participate in protocol development teams for the new HIV screening protocol and other new protocols, and continue leadership, training, and dissemination efforts at the national and local levels. We will also continue to encourage and seek outside funding for studies conducted on the CTN platform.