Cancer Center Support Grant

描述（由申请人提供）：印第安纳州大学癌症中心是一个矩阵癌症中心，组织和促进癌症研究，教育，患者护理，癌症控制和预防，以完成其降低印第安纳州及其他地区癌症发病率，发病率和死亡率的使命。 该申请旨在为该中心的五个研究项目，十一个共享设施，协议特定研究和协议审查和监测系统提供资金。 此外，还要求为行政、方案规划和评价、发展基金和高级领导人提供资金。 研究项目的组织和开发具有高度的互动性，使基础和临床研究人员之间能够成功合作。 研究项目包括：1）行为肿瘤学和癌症预防，2）乳腺癌，3）实验治疗，3）造血和免疫学，5）细胞生长调节。 支持这些计划的成员是十一个共享资源：生物显微镜，生物统计学和数据管理，临床研究办公室，基因分型和基因表达，流式细胞术，病理学，体内成像，蛋白质组学和蛋白质表达，转基因和敲除小鼠核心，移植和异种移植小鼠核心，载体生产。

DESCRIPTION (provided by applicant): The Indiana University Cancer Center is a matrix Cancer Center that organizes and facilitates cancer research, education, patient care, and cancer control and prevention to accomplish its mission of reducing the incidence, morbidity, and mortality of cancer in Indiana and beyond. This application seeks funds for the Center's five research programs, eleven shared facilities, Protocol-Specific Research, and a Protocol Review and Monitoring System. In addition, funds are requested for Administration, Program Planning and Evaluation, Developmental Funds, and Senior Leaders. The research programs have been organized and developed to be highly interactive, allowing for successful collaboration among basic and clinical researchers. The research programs are: 1) Behavioral Oncology and Cancer Prevention, 2) Breast Cancer, 3) Experimental Therapeutics, 3) Hematopoiesis and Immunology, and 5) Regulation of Cell Growth. Supporting the members of these programs are eleven shared resources: Biological Microscopy, Biostatistics and Data Management, Clinical Research Office, Genotyping and Gene Expression, Flow Cytometry, Pathology, In Vivo Imaging, Proteomics and Protein Expression, Transgenic and Knock-out Mouse Core, Transplant and Xenograft Mouse Core, and Vector Production.