Assessment of the Exposure to Methylmercury in Fish among

甲基汞是一种强有力的神经毒素，特别是对胎儿和幼儿(1至6岁)。 据报道，海洋中的许多鱼类、佛罗里达大沼泽地和海洋中的甲基汞含量都很高 佛罗里达州南部的某些周边运河。目前还没有高危人群的最新数据， 特别是在南佛罗里达州的孕妇和幼儿中。这项拟议的初步研究的目标是 是测量来自海洋、大沼泽地和南佛罗里达运河的鱼类中甲基汞的含量， 和评估鱼类的消费模式，并测量中国人头发中甲基汞的含量 经常食用被甲基汞污染的鱼的孕妇和幼儿。这个 假设是被甲基汞污染的鱼对人体负担有很大贡献 与其他美国人口的身体负担相比，南佛罗里达州的低收入消费者。这 假设将通过追求两个具体目标来检验：1)从以下几个方面确定鱼中甲基汞的含量 海洋、大沼泽地和南佛罗里达运河；以及2)决定了频繁的 食用这些受污染的鱼与孕妇和年轻人的甲基汞水平过高有关 住在南佛罗里达的孩子们。在第二个目标下，将向 参与者和/或他们的父母或监护人评估他们的鱼类消费模式，以及头发样本 从研究对象中将分析甲基汞的含量。这项拟议的研究具有重要意义 因为预计它将促进和扩大对当地甲基汞水平有多高的理解 海洋、大沼泽地和南佛罗里达运河的鱼类通过鱼类消费模式达到高水平 迈阿密戴德县孕妇和幼儿中的甲基汞水平。

Methyl mercury is a potent neurotoxin, particularly to fetuses and young children (from one to six years of age). Methyl mercury levels are reportedly high in numerous fish species in the ocean, the Florida Everglades and certain surrounding canals in South Florida. There are no recent data in high risk human populations, particularly in pregnant women and young children in South Florida. The objective of this proposed Pilot Study is to measure the content of methyl mercury in fish from the ocean, the Everglades and South Florida canals, and to assess the fish consumption patterns and to measure the content of methyl mercury in the hair of pregnant women and young children who frequently consume fish contaminated with methyl mercury. The hypothesis is that methylmercury-contaminated fish represents a significant contribution to the body burden in South Florida low-income consumers as compared to the body burden in other U.S. populations. This hypothesis will be tested by pursuing two specific aims: 1) Determine the content of methyl mercury in fish from the ocean, the Everglades and South Florida canals; and 2) Determine the extent to which frequent consumption of these contaminated fish is related to high methyl mercury levels in pregnant women and young children living in South Florida. Under the second aim, a survey questionnaire will be administered to the participants and/or their parents or guardians to assess their fish consumption patterns, and samples of hair from the study subjects will be analyzed for methyl mercury content. The proposed research is significant because it is expected to advance and expand the understanding of how high local levels of methyl mercury in the fish of the ocean, Everglades and South Florida canals lead through fish consumption patterns to high methyl mercury levels in pregnant women and young children in Miami Dade County.