Identification and Therapy of Postpartum Depression

描述（由申请人提供）：围产期抑郁症是一个主要的公共卫生问题。产后抑郁症（PPD）导致个人和家庭的痛苦时，适应父母是关键。在医疗环境中治疗抑郁症的成功干预措施已被慢性病管理模式所框定。成功的关键因素是一个专门的护理经理，他为患者提供教育和支持，积极协调护理，从而改善患者的治疗效果。 与医疗办公室环境中的干预措施相比，定位于健康计划一级的电话护理管理为患有产后抑郁症的妇女提供了持续治疗支持的系统和有效机制，特别是在地理上分散的人群中。 我们建议进行一个全面的项目，以改善抑郁症产后妇女的治疗效果，通过适应在初级保健环境中使用的抑郁症护理管理模式。主要组成部分是：1）产后妇女人群的抑郁症筛查，2）对所有筛查阳性的妇女进行抑郁症教育，3）对在筛查工具上得分高于和低于定义阈值的妇女进行诊断性访谈以评估抑郁症，4）基于电话的护理管理干预与常规护理的随机对照试验，以及，5）对出生后第一年的抑郁症和母婴公共卫生结果进行纵向评估。该项目中的所有妇女都有资格通过两个健康计划（社区护理行为健康组织和Highmark）获得心理健康服务。两者都为医疗补助和商业会员服务。我们计划识别同意随机分配到抑郁症护理管理干预或常规护理组的PPD患者（n=462）。他们将在选择抑郁症治疗方面得到支持（在接受有关选择的教育后），鼓励他们获得首选的治疗（通过直接讨论障碍和解决方案），建议遵守治疗建议，并协助解决问题，如果未能作出反应。两组将在出生后3个月、6个月和12个月进行系统评价。结果不仅包括产妇抑郁症状水平，还包括母亲，家庭和婴儿的功能和公共卫生结果。我们已经建立了一个多学科的团队，在临床研究与抑郁症和少数民族妇女和健康服务，以满足这些需求的专业知识。

DESCRIPTION (provided by applicant): Depression during the perinatal period is a major public health concern. Postpartum depression (PPD) causes personal and family suffering at a time when adaptation to parenthood is critical. Successful interventions for treating depression in medical settings have been framed by a chronic disease management model. The key ingredient to success is a dedicated care manager who provides education and support to patients, actively coordinates care, and thereby improves treatment outcomes for patients. Compared to interventions in medical office settings, telephone care management positioned at the level of the health plan offers a systematic and efficient mechanism for ongoing treatment support of women with PPD, particularly in a geographically dispersed population. We propose to conduct a comprehensive project to improve treatment outcomes for depressed postpartum women through adaptation of the depression care management model used in primary care settings. The major components are: 1) depression screening in a population of postpartum women, 2) depression education for all who screen positive, 3) a diagnostic interview to evaluate for depressive disorders in women who score above and below a defined threshold on the screening instrument, 4) a randomized controlled trial of telephone-based care management intervention vs. usual care for depression, and, 5) longitudinal evaluation across the first year post-birth for depression and maternal and child public health outcomes. All women in this project will be eligible for mental health services through two health plans (Community Care Behavioral Health Organization and Highmark). Both serve Medicaid and commercial members. We plan to identify women with PPD (n=462) who agree to be randomly assigned to the depression care management intervention or a usual care group. They will be supported in making choices about depression treatment (after receiving education about options), encouraged to access their preferred treatment (through the direct discussion of barriers and solutions), counseled to comply with treatment recommendations, and assisted to problem-solve if failure to respond occurs. Both groups will have systematic evaluations at 3, 6, and 12 months post-birth. Outcomes include not only maternal depressive symptom levels but also functional and public health outcomes for mothers, families, and infants. We have developed a multi-disciplinary team with expertise in clinical research with depressed and minority women and health services to address these needs.