Stanford - South Africa Biomedical Informatics Program

最近广为人知的疾病暴发表明有必要增加生物医学的能力 ‘.社区收集、管理和快速交换跨越全球基础生物学和医学的数据。 作为抗击人类免疫缺陷病毒(HIV)等流行病的全球战略的一部分，有一个 尚未满足发展和支持培训有效、合乎道德的生物医学信息学的能力的需要 受影响最严重的国家的研究人员。我们的建议通过利用最近的 在南非西开普省大学(UWC)建立的生物信息学培训计划 向生物医学信息学课程发展，并直接应对训练有素的严重短缺 在南非的教员。一个有重点的发展计划将使人们能够通过长期的 在斯坦福大学建立生物医学信息学项目，做出重大和可持续的贡献 针对UWC现有教职员工已经发现的缺陷。这项提案的重点是 通过三个机制开发新的培训者：1)通过联合开发和 斯坦福大学教授的短期课程，2)在UWC为受训人员提供支持，培养当地教学人才，3) 通过支持丰富生物医学信息学的研究社区和开发新的课程材料 斯坦福大学UWC的访问学者和学生。 该方案支持的高度优先项目包括开发南非国家艾滋病毒 数据库建立在国立卫生研究院资助的UWC现有倡议的基础上，以满足基因学家的需求， 流行病学家和医疗界。有关HIV基因组变异和患者的信息 将收集对各种抗病毒治疗的反应，并开发新的或改进的治疗方法作为 结果。以前，需要这样一个数据库来支持NIH资助的Caprisa项目 通过美国国立卫生研究院资助的CAPRISA计划(www.caprisa.org)，已经确定并获得了初步支持。

Recent highly publicized disease outbreaks illustrate the need to increase the capacity of the biomedical '.ommunity to collect, manage and rapidly exchange data that spans basic biology and medicine worldwide. As part of a global strategy to combat epidemics, such as human immunodeficiency virus (HIV), there is an unfulfilled need to develop and support the capacity to train effective, ethical biomedical informatics researchers in the countries most affected. Our proposal addresses this need by leveraging the recently established, bioinformatics training program at the University of the Western Cape (UWC), South Afdca to evolve towards a Biomedical Informatics program and responds directly to the acute shortage of trained faculty in South Africa. A focused development program will enable experience gained through the long- established Biomedical Informatics program at Stanford University to contribute significantly and sustainably towards shortcomings that have been identified by the existing faculty at UWC. This proposal focuses on developing new trainers by three mechanisms: 1) Extend the graduate curriculum with jointly developed and taught short courses from Stanford, 2) develop local teaching talent with support for trainees at UWC, and 3) enrich the research community and develop new curricular matedal in biomedical informatics by supporting Visiting Scholars and students from UWC at Stanford University. High priority projects supported by this program include development of a South African National HIV Database that builds upon an existing NIH funded initiative at UWC to serve the needs of genomicists, epidemiologists and the health care community. Information about HIV genomic variations and patient responses to various antiviral therapies will be collected and new or improved treatments developed as a result. The need for such a database to support the NIH-funded Caprisa project has previously been identified and initial support has been gained through the NIH-funded CAPRISA program (www.caprisa.org).