Radicals in unconventional media - improving the sustainability of radical reactions through next generation ionic liquid radical chemistry

尽管在过去的几十年里取得了重大进展，但许多自由基反应仍然在有机溶剂中进行，这些溶剂通常是有毒的，易燃的，难以回收的，并且使用了不需要的试剂。这是及时的，新的自由基化学的发展，远离这种“传统”的景观。本提案将发展自由基如何与（非常规）离子液体溶剂相互作用和反应的基本理解。这种认识反过来将导致新的、更有效的自由基方法的发展，用于制备包括生物分子在内的重要材料。减少自由基化学对环境的影响是本研究的最终目的。

Despite significant advances over the past few decades, many free radical reactions are still carried out in organic solvents that are often toxic, flammable, difficult to recycle and employ undesirable reagents. It is timely that new free radical chemistry be developed that moves away from this "conventional" landscape. This proposal will develop a fundamental understanding of how free radicals interact with, and react in, (unconventional) ionic liquid solvents. This understanding will lead, in turn, to the development of new, more efficient, free radicals methods for the preparation of important materials that include biomolecules. Reduced environmental impact of free radical chemistry is the ultimate aim of this work.