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ULTRASTRUCTURE OF APOPTOTIC MITOCHONDRIA

ULTRASTRUCTURE OF APOPTOTIC MITOCHONDRIA
凋亡线粒体的超微结构
批准号:
7358055
负责人:
DONALD DAVID NEWMEYER
金额:
$0.51万
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-05-01 至 2007-04-30

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中文摘要
翻译
这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金,因此可能会出现在其他CRISE条目中。列出的机构是针对中心的,而不一定是针对调查员的机构。具体目标:我们正在设计一种新的方案,在冷冻/解冻过程中保存分离的线粒体。我们的具体目标是开发一种方法,使冷冻哺乳动物线粒体的长期保存成为可能,从而为利用分离的线粒体进行研究和大规模筛选开辟了巨大的可能性。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Specific Aims: We are designing a new protocol to preserve isolated mitochondria during freeze/thaw manipulations. Our specific aim is to develop a method that makes possible the long-term storage of frozen mammalian mitochondria and consequently open large possibilities for research and large-scale screening using isolated mitochondria.
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ACTIVATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION BY BH3-ONL
Mitochondria, apoptosis and the Bcl-2 family
  • 批准号:
    8077521
  • 项目类别:
  • 资助金额:
    $8.49万
  • 财政年份:
    2010
  • 负责人:
    DONALD DAVID NEWMEYER
  • 依托单位:
ACTIVATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION BY BH3-ONL
ACTIVATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION BY BH3-ONL
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