PATHOGEN RELATED PROTEIN STRUCTURES

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。病原体(支原体)蛋白或其同系物的结构为药物开发提供了关键信息。我们已经结晶了各种病原体蛋白及其同源物。将Se-Met加入到蛋白质样品中进行MAD相变。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The structures of pathogen (mycoplasma) proteins or their homologues provide critical information to drug discovery. We have crystallized various pathogen proteins and their homologues. Se-Met is incorporated into the protein sample for MAD phasing.