MEASUREMENT OF HBNO IN VENOUS BLOOD IN HUMANS BY ELECTRON PMRS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本初步研究的主要目的是评估我们是否可以使用电子顺磁共振波谱检测健康志愿者和慢性心力衰竭患者静脉血中总HbNO水平在静脉注射硝酸甘油剂量增加后的增加

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of this pilot study is to evaluate whether we can detect an increase in total HbNO levels in venous blood of healthy volunteers and patients with chronic heart failure using electon paramagnetic resonance spectroscopy following increasing doses of intravenous nitoplycerin trea