MEASUREMENT OF HBNO IN VENOUS BLOOD IN HUMANS BY ELECTRON PMRS

通过电子 PMRS 测量人体静脉血中的 HBNO

• 批准号: 7625604
• 负责人: JO ELLEN RODGERS
• 金额: $ 0.06万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7625604
• 关键词: Blood; Chronic; Computer Retrieval of Information on Scientific Projects Database; Dose; Electron Spin Resonance Spectroscopy; Electrons; Funding; Grant; Heart failure; Human; Institution; Intravenous; Measurement; Patients; Pilot Projects; Research; Research Personnel; Resources; Source; Spectrum Analysis; United States National Institutes of Health; Venous; glycosylated-nitric oxide complex hemoglobin A; healthy volunteer

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of this pilot study is to evaluate whether we can detect an increase in total HbNO levels in venous blood of healthy volunteers and patients with chronic heart failure using electon paramagnetic resonance spectroscopy following increasing doses of intravenous nitoplycerin treatment.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项初步研究的主要目的是评估我们是否可以检测到总HbNO水平的增加，在健康志愿者和慢性心力衰竭患者的静脉血中使用电子顺磁共振光谱增加剂量的静脉硝酸甘油治疗。