FAMILY BONDS AMP; OXYTOCIN: CARDIOVASCULAR STRESS BUFFERS

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。本研究的目的是考察高生活压力和来自他人的低支持与工作和家庭动态血压升高的关系，以及在实验室和家庭压力下血压升高和血管收缩的关系。另一个目的是研究这些性状与儿茶酚胺(肾上腺素)反应增加、交感神经系统激活、不良血脂(胆固醇)谱、激素水平(雌激素、催产素、皮质醇和睾酮)以及心脏和血管结构变化的关系。在这一阶段的研究中，重点关注与他人互动的压力，以及可能增加或减少压力感的自然荷尔蒙反应。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to examine the relationships of high life stress and low support from others to elevated ambulatory blood pressure at work and at home and elevated blood pressure and constriction of vessels during stress in the lab and at home. An additional purpose is to examine the relationships of these traits to increased catecholamines (adrenaline) responses, sympathetic nervous system activation, adverse lipid (cholesterol) profiles, hormone levels (estrogen, oxytocin, cortisol, and testosterone) and cardiac and vascular structural changes. In this phase of the study, the focus is on stress involved in interactions with others, and natural hormonal responses which may increase or decrease feelings of stress.