RACE AND CONTROL OF TISSUE RENIN-ANGIOTENSIN SYSTEM: IDENTIFYING CAUSAL GENES

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的目的是解释黑人高血压及其并发症的患病率高于白种人。有待验证的假设是，黑人的肾脏激素中肾素-血管紧张素系统的活性增加，这是由遗传因素决定的。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to explain the higher prevalence of high blood pressure and its complications in blacks than in caucasians. The hypothesis to be tested is that blacks have increased activity of the renin-angiotensin system in hormones in their kidneys, which is determined by genetic factors.