ULTRAVIOLET A LIGHT ON DISEASE ACTIVITY AND IMMUNE FUNCTION/LUPUS ERYTHEMATOSUS

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究的目的是确定长期低剂量超a1 （320-400 nm）光对延迟型超敏反应、亚群t淋巴细胞的影响，以及通过体外淋巴细胞测定正常人t淋巴细胞功能的影响。将对系统性红斑狼疮患者进行相同的观察，并测量该光源对SLE实验室和临床参数的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine the effects of long-term low dose ultra-A1 (320-400 nm) light on delayed type hypersensitivity, T-lymphocyte of subset populations, and t-lymphocyte function of normal human subjects as determined by in vitro lymphocyte assays. The same observations will be made on patients with systemic lupus erythematosus and the effects of this light on the laboratory and clinical parameters of SLE will be measured.