ETHNIC VARIATIONS IN ANTIDEPRESSANT RESPONSE

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。确定非裔美国人和白种人抑郁症患者的基因特征如何影响他们对研究药物celexa的反应。Celexa是一种已知有助于改善人的情绪的药物，并已被fDA批准用于治疗抑郁症。本研究还将研究社会经济变量在决定病程和治疗反应方面的影响，以及其他基因的影响，这些基因也可能影响这两组对抗抑郁药celexa的治疗反应

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To determine how the genetic profile of African American and Caucasian depressed patients influence their responses to the study medication celexa. Celexa is a medication that is known to help improve a person's mood and has been approved by the fDA to use in the treatment of depression. This study will also examine the influence of socioeconomic variables in determining the course and treatment response and the influence of other genes that may also affect the therapeutic response of these two groups to the antidepressant celexa