COLLAGENASE IN THE TREATMENT OF DUPUYTREN'S DISEASE

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。一项II期随机、安慰剂双盲试验正在研究注射胶原酶作为Dupuytren病（一种手部固定屈曲挛缩畸形）的非手术治疗。这种治疗方法可能会减少Dupuytren病的手术筋膜切除术的需要。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. A Phase II random, placebo double blind trial of injectable collagenase is being studied as a non-operative treatment for Dupuytren's disease, a fixed flexion contracture deformity of the hand. This therapy may obviate the need for surgical fascioectomy for Dupuytren's disease.