EFFECTS OF PATTERNS OF WEIGHT LOSS AND VARIABLES ON CHANGES IN RMR

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。本研究项目的具体目的是探索可能促进减肥和长期维持减肥的两个因素：减肥模式（连续或间歇性的少量减肥和2周的体重维持）和程序变量（传统的减肥和规定饮食和行为改变的组与强调条件对受试者的意义和准备改变的体重管理组）。这两个因素在体重管理的研究文献中尚未得到充分的探讨。由于肥胖和合并症的患病率不断上升，以及相关的医疗保健费用不断增加，这种性质对研究的贡献是重要的。[1]通过确定上述两个因素是否与改善长期维持减肥效果有关，可以进一步开展工作，以增加对最大化长期减肥策略的研究文献。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The specific aim of this research project is to explore 2 factors that may facilitate weight loss and long term maintenance of weight loss: patterns of weight loss (continuous vs. intermittent periods of small amounts of weight loss and 2-week periods of weight maintenance), and program variables (traditional weight loss and group with prescribed diets and behavior modifications vs. weight management group that emphasises meaning of the condition to the subject and readiness to change). These two factors have been under-explored in the research literature on weight management. Contributions of this nature to the research are important due to the increasing prevalence of obesity and co-morbidities, as well ad the associated increasing health care costs. [1] By determining if the two factors noted above are associated with improved long term maintenance of weight loss, further work can be pursued to add to the body of research literature on strategies to maximize long term weight loss.