FAMILIAL MELANOMA RESEARCH CLINIC (FMRC)

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。据估计，在2000年出生的美国人中，每75人中就有1人会在一生中患上黑色素瘤。报告显示，8-12%的黑色素瘤发生在家庭群体中，那些有一级亲属患有黑色素瘤的人被认为患黑色素瘤的风险增加了2-3倍。我们已经建立了一个高风险黑色素瘤诊所（家族黑色素瘤研究诊所，FMRC），作为一个“核心”设施，提供一种机制，调查具有遗传风险的黑色素瘤家庭。这个诊所是模仿犹他大学高风险乳腺癌和家族性结肠癌诊所的模式建立的，犹他大学高风险乳腺癌和家族性结肠癌诊所为研究遗传性癌症提供了完善的模型

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. It is estimated that one out of every 75 people born in the U.S. in the year 2000 will get a melanoma in his/her lifetime. Reports indicate that between 8-12% of melanomas occur within family groups and those people having a first degree relative with melanoma are considered to have a 2-3 fold increased risk of developing melanoma. We have established a high-risk melanoma clinic (Familial Melanoma Research Clinic, FMRC) that acts as a "core" facility to provide a mechanism for investigation of families with an inherited risk of melanoma. This clinic was patterned after the preexisting University of Utah High Risk Breast and Familial Colon Cancer Clinics that provided well-established models for the investigation of inherited cance