OUTCOME AFTER SURGICAL CORRECTION OF ANORECTAL MALFORMATIONS

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。肛门直肠畸形是一种罕见的先天性缺陷，发生率约为1/5000活产。所有患有这些畸形的患者都有排便的终身问题，因此，可能会遭受严重的社会和身体疾病。虽然大便失禁评分系统已被描述为成人解剖大便失禁，还没有进行研究，以开发类似的评分系统，在儿童大便失禁由于肛门直肠畸形。本研究的目的是验证一种新的肛门直肠畸形患儿大便失禁评分系统。将接受肛门直肠畸形手术的患者与两个对照组进行比较：遗尿儿童和无尿失禁或大便失禁病史的儿童。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Anorectal malformations are uncommon congenital defects, occurring approximately 1 in 5000 live births. All patients with these malformations have lifelong problems with defecation, and, as a result, can suffer great social and physical morbidity. Although fecal incontinence scoring systems have been described in adults with anatomic fecal incontinence, there have been no studies performed to develop similar scoring systems in children with fecal incontinence due to anorectal malformations. The purpose of this study is to validate a new fecal incontinence scoring system for children with anorectal malformations. Patients who have undergone surgery for anorectal malformations will be compared to two control groups: children with eneuresis and children with no history of urinary or fecal incontinence.