CLINICAL IMPLICATIONS OF BODY CELL MASS AND METABOLIC CHANGES IN HIV INFECTION

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。这项研究将是一项描述性的初步研究，调查在接受睾酮（或类似）治疗的hiv感染者体内成分和静息能量代谢的变化。主要重点将是验证用于量化体细胞质量（BCM）和REE变化的现场技术，特别关注调查几个已发表的单频生物电阻抗分析方程的有效性和一种有前途的替代方法，称为生物阻抗谱。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study will be a descriptive pilot study investigating changes in body composition and resting energy metabolism in HIV-infected individuals who have been prescribed testosterone (or similar) therapy. The primary focus will be to validate field techniques for quantifying changes in body cell mass (BCM) and REE, with particular attention to investigating the validity of several published single-frequency bioelectrical impedance analysis equations and a promising alternative method called bioimpedance spectroscopy.