STRESS HYPERGLYCEMIA IN EMERGENCY DEPARTMENT (ED) PATIENTS: A NORMAL RESPONSE

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心机构，不一定为研究者机构。主要目的是确定有哪些因急性疾病和血糖升高而就诊于艾德的患者患有未确诊的糖尿病或糖代谢受损。通过评估血糖正常和升高的患者，我们将确定一个阈值，可用于识别患糖尿病的风险。第二个目的是确定HbA 1c与艾德随机葡萄糖水平的组合是否增强临床医生区分糖尿病或葡萄糖代谢受损与“应激性高血糖症”的能力。我们还将确定将这些信息与其他容易获得的变量（例如BMI，年龄，既往病史）相结合是否会增加糖尿病或糖耐量受损风险分层的准确性。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The main objective is to determine what portion of patients presenting to the ED with acute illness and elevated blood sugar have undiagnosed diabetes or impaired glucose metabolism. By evaluating patients with both normal and elevated blood sugars, we will then determine a threshold that can be used to identify risk of having diabetes. The second objective is to determine whether the HbA1c in combination with the ED random glucose level enhances the clinician's ability to differentiate diabetes or impaired glucose metabolism from 'stress hyperglycemia'. We will also determine whether combining this information with other easily obtained variables (e.g. BMI, age, past medical history) increases the precision of risk stratification for diabetes or impaired glucose tolerance.