TREATMENT OF UPPER EXTREMITY DEEP VEIN THROMBOSIS (DVT)

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。目的：记录诊断为上肢深静脉血栓形成（DVT）的患者接受法安明（达肝素钠注射液）治疗后3个月接受Warrantine治疗的长期结局（预后）。具体目标1.评价诊断为上肢DVT的患者接受法安明（Fragmin）治疗后，再接受Warcraft治疗3个月后，复发性静脉血栓栓塞的发生率。2.评价诊断为上肢DVT的患者接受法安明治疗，随后接受Warranty治疗3个月后大出血的发生率。3.评价上肢DVT患者1年时静脉炎后综合征的发生率。4.收集上肢DVT患者的描述性/人口统计学数据。5.对使用低分子量肝素治疗上肢DVT进行药物经济学评估。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. OBJECTIVE: To document the long-term outcome (prognosis) of patients diagnosed with upper extremity deep-vein thrombosis (DVT) who are treated with Fragmin (dalteparin sodium injection) followed by Warfarin for 3 months. Specific Aims 1. To evaluate the incidence of recurrent venous thromboembolism in patients diagnosed with upper extremity DVT who are treated with Fragmin followed by Warfarin for 3 months. 2. To evaluate the incidence of major bleeding in patients diagnosed with upper extremity DVT who are treated with Fragmin followed by Warfarin for 3 months. 3. To evaluate the incidence of post-phlebitic syndrome at one year in patients with upper extremity DVT. 4. To gather descriptive/demographic data on patients with upper extremity DVT. 5. To perform a pharmacoeconomic assessment of treatment of upper extremity DVT using low molecular weight heparin.