Planning Grants for Institutional Clinical and Translational Science Awards

描述（由申请人提供）：NIH重新设计临床研究企业的努力为学术医疗中心提供了一个机会，将其临床研究基础设施重组为一个综合的机构。总体目标是提高临床和转化研究的质量和效率，并支持培训新的临床和转化科学研究人员。本提案的目的是规划活动，设计马里兰大学（UM）临床和转化科学研究中心（CTSRC）。这些活动将包括为中心的内容、治理、管理和评估制定计划。此外，规划过程将包括影响UMB的文化变革，以启动团队科学和临床和转化科学的离散学科的概念。马里兰大学巴尔的摩分校拥有CTSRC的许多要素，包括一个忠诚的临床医生、科学家和管理团队，以提供领导，以及合作机构，以确保多学科参与。这些机构包括澳大医学院、牙科学院、药学院、护理学院、社会工作学院、法学院以及研究生院。此外，澳大还获得了K30临床研究硕士课程发展奖和K12多学科临床研究职业发展路线图奖。我们计划在临床和转化研究中建立一个类似T-32的项目。我们的规划过程将围绕四个委员会的工作展开：执行委员会、培训/职业发展/试点研究委员会、资源和服务委员会以及内部咨询委员会。这一过程将包括需求评估、计划撤退以及对其他资助的临床和转化科学获奖者的实地考察。规划拨款将支持确定CTSRC组成部分的努力，特别是在新方法、生物信息学、研究设计和生物统计学、监管支持、参与者和临床互动、社区参与、培训和职业发展等领域。

DESCRIPTION (provided by applicant): The NIH effort to Re-engineer the Clinical Research Enterprise provides an opportunity for academic medical centers to reorganize their clinical research infrastructures into an integrated institutional home. The overarching goal is to enhance the quality and efficiency of clinical and translational research and to support the training of new clinical and translational science investigators. The purpose of this proposal is to plan activities to design the University of Maryland (UM) Clinical and Translational Science Research Center (CTSRC). These activities will include developing plans for the content, governance, administration, and evaluation of the Center. In addition, the planning process will include effecting the cultural changes at UMB needed to launch the concepts of team science and the discrete discipline of clinical and translational science. The University of Maryland Baltimore has many of the elements of a CTSRC, including a committed clinician scientist and administrative team to provide leadership as well as collaborating institutions to ensure multidisciplinary participation. These institutions include the UM Schools of Medicine, Dentistry, Pharmacy, Nursing, Social Work, and Law as well as the Graduate School. In addition, UM has both a K30 Curriculum Development Award with a Masters Degree in Clinical Research and a Roadmap K12 Award for Multidisciplinary Clinical Research Career Development. We plan to build a T-32 like program in clinical and translational research. Our planning process will be built around the work of 4 committees: an Executive Committee, Training/Career Development/Pilot Studies Committee, Resources and Services Committee, and an internal advisory committee. The process will include a needs assessment, planning retreat, and site visits to other funded clinical and translational science awardees. The planning grant will support efforts to identify components of the CTSRC particularly in the areas of novel methodologies, bioinformatics, study design and biostatistics, regulatory support, participant and clinical interactions, community engagement, and training and career development.