Bridging Efficacy and Effectiveness in Drug Abuse Treatment

说明(由申请者提供)：本提案的总体目标是支持申请者在药物滥用治疗干预措施开发领域继续发展成为一名新的独立研究精神病学家。提交这份K02是为了继续申请人以K23开始的发展，这允许他在这个领域获得独立的研究支持。在过去的五年里，申请人一直在进行成瘾障碍领域的治疗开发、流行病学和服务研究。通过K02奖项，申请者寻求深化这一工作，同时继续发展他的职业生涯。拟议的研究方案的统一主题是开发干预措施，以改善有和没有共生障碍的成瘾患者的结果。该方案的重点将是开发可在社区环境中使用的干预措施，从而将效力和效力联系起来。这款K02是围绕三个项目打造的。第一个项目“SMART：改善药物滥用诊所精神疾病的检测和治疗”(DA020783)的目标是开发一种干预措施，以解决社区诊所治疗共生疾病的主要障碍。由纽约州酒精和药物滥用服务办公室资助的第二个项目“青少年病理性赌博的治疗”的目标是为这一群体开发一种手册CBT。第三个项目“拉美裔美国人的药物滥用”(DA019606)寻求为制定拉美裔预防和治疗方案奠定经验基础。成瘾领域需要临床医生--能够在疗效和有效性研究之间架起桥梁的研究人员，该奖项将允许通过与这些领域的专家合作和培训，提高申请者在成功开展这项工作所需方法方面的技能。申请者职业计划的其他部分包括行为干预策略的高级培训、生物统计学和继续进行道德培训。最后，申请者将为各种教育活动做出贡献，并承担越来越重要的指导角色。在申请者所在机构的大力支持下，本申请中提议的活动的计划结果将是发展一位能够规划和进行研究的科学家，该研究将在成瘾障碍的治疗中架起有效性和有效性的桥梁。

DESCRIPTION (provided by applicant): The overall aim of this proposal is to support the continuing development of the applicant as a newly independent research psychiatrist in the field of interventions development for drug abuse treatment. This K02 is submitted to continue the applicant's development initiated with a K23, which permitted him to obtain independent research support in this field. Over the last five years the applicant has been conducting studies of therapy development, epidemiology and services research in the area of addictive disorders. Through the K02 award, the applicant seeks to deepen this line of work while continuing the development of his career. The unifying theme of proposed program of research is the development of interventions to improve the outcome of addictions with and without co-occurring disorders. The emphasis of the program will be on development of interventions that can be used in community settings and, thus, bridge efficacy and effectiveness. This K02 is built around three projects. The goal of the first project, "SMART: Improving Detection and Treatment of Psychiatric Comorbidity in Substance Abuse Clinics" (DA020783), is to develop an intervention to address key barriers to the treatment of co-occurring disorders in community clinics. The goal of second project, "Treatment for Adolescents with Pathological Gambling" funded by the New York State Office of Alcohol and Substance Abuse Services, is the development of a manualized CBT for this population group. The third project "Substance Abuse in Hispanics" (DA019606) seeks to establish an empirical foundation to develop prevention and treatment programs for Hispanics. The field of addiction needs clinicians-researchers who can bridge efficacy and effectiveness research, and this award will permit enhancement of the applicant's skills in the methods necessary to successfully conduct this work, through collaboration and training with experts in these fields. Other components of the applicant's career plan include advanced training in behavioral intervention strategies, biostatistics and the continuation of ethics training. Finally, the applicant will contribute to various educational activities and assume a progressively more important mentoring role. The planned outcome of the activities proposed in this application, with the strong support of the applicant's institution, will be the development of a scientist capable of planning and conducting research that will bridge efficacy and effectiveness in the treatment of addictive disorders.