Family-Based HIV Prevention for Latinos

描述(申请人提供)：在被诊断为艾滋病毒携带者中，拉美裔占了不成比例的比例，拉美裔青少年面临着从事可能导致艾滋病毒的性行为的风险。然而，与其他族裔群体不同的是，关于针对拉丁裔青少年的艾滋病毒预防干预措施的数据迄今尚未公布。该K奖将对专门针对拉丁裔家庭的以家庭为基础的干预进行初步研究。在NIMH少数民族补充奖的支持下，莱斯卡诺博士从一项针对非少数民族青年的多点试验中调整了一种基于家庭的干预措施。莱斯卡诺博士采用定性的方法，在干预措施中增加了与拉美裔相关的家庭背景问题，如文化适应、宗教信仰、性别角色和性社会化、亲子沟通和监督做法。K奖的第一阶段将是经过调整的以家庭为基础的干预措施的演练，有三个队列(每组8个家庭)，以进一步评估参与者的反应和适当性。然后，将根据结构化离职面谈的反馈修改干预措施。接下来，100个青少年年龄在13岁至18岁之间的拉丁裔家庭将被随机分为以家庭为基础的艾滋病毒预防干预措施或侧重于饮食和锻炼等健康行为的一般健康促进(GHP)条件。小组由6至8名家长和青少年组成，为期一天，时长7小时。这两种干预措施分别为青年和家长开展活动(例如，关注青少年的脆弱性)，并将家长和青少年放在一起。该项目将通过评估青少年与艾滋病毒相关的性行为和态度、性别和性社会化、亲子交流和父母监测的变化，来估计以拉丁裔家庭为基础的艾滋病毒预防干预措施的效果。措施将在基线以及干预后3个月和6个月完成。K奖所做的工作将提供试点数据，这些数据将导致提交R01，以确定干预措施的有效性，而不是在更大的拉丁裔样本中，只针对青少年、以技能为基础的艾滋病毒预防小组和一般健康促进小组。拉美裔社区迫切需要一种有效的干预。

DESCRIPTION (provided by applicant): Latinos are disproportionately represented among those diagnosed with HIV and Latino adolescents are at risk for engaging in sexual behaviors that can lead to HIV. However, data regarding HIV prevention interventions for Latino adolescents, as distinct from other ethnic groups, have not been published to date. This K Award will conduct an initial study of a family-based intervention specifically for Latino families. With the support of a NIMH Minority Supplement Award, Dr. Lescano has adapted a family-based intervention from a multi-site trial for non-minority youth. Using a qualitative approach, Dr. Lescano has added to the intervention family context issues relevant to Latinos such as acculturation, religiosity, gender role and sexual socialization, parent-child communication, and monitoring practices. The initial phase of the K Award will be a run-through of the adapted family-based intervention with three cohorts (8 families per group) to further assess participant reaction and appropriateness. The intervention will then be revised based on feedback using structured exit interviews. Next, 100 Latino families with an adolescent between the ages of 13 and 18 will be randomized into either the family based HIV prevention intervention or a general health promotion (GHP) condition that focuses on healthy behaviors such as diet and exercise. Groups consist of 6 to 8 parent and youth dyads in a one-day, 7-hour workshop. Both interventions employ activities for youth and parents separately (e.g., focus on adolescent vulnerability) and parents and adolescents together. The project will estimate the effect size of the Latino Family-based HIV prevention intervention from assessment of changes in the adolescents' HIV-related sexual behavior and attitudes, gender and sexual socialization, parent-child communication, and parental monitoring. Measures will be completed at baseline and at 3 and 6 months post-intervention. The work done in this K Award will provide pilot data that will lead to submission of an R01 to determine the efficacy of the intervention, compared to a adolescent-only, skills-based HIV prevention group and a general health promotion group, in a larger sample of Latinos. An efficacious intervention is urgently needed for Latino communities.