ADMINISTRATIVE CORE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 夏威夷大学临床研究中心(UH CRC)成立于1995年，由太平洋生物医学研究中心(PBRC)、夏威夷大学(UH)约翰·A·伯恩斯医学院(JABSOM)和卡皮奥拉尼妇女儿童医学中心(KMCWC)合作建立。自该计划开始以来，UH CRC一直在KMCWC运营一家门诊研究诊所，该诊所一直是其临床活动的主要基地。在当前的资金周期内，UH CRC已扩大到包括皇后区医疗中心(QMC)的磁共振(MR)核心实验室，目前正在计划在QMC开发一个新的门诊研究诊所。该计划还扩大到包括与利希医院的夏威夷艾滋病临床研究计划(HACRP)一起的艾滋病毒研究核心，并正在推进在夏威夷凯撒永久健康研究中心(CHRH)开发生物营养研究核心的计划。最后，通过建立临床研究开发项目(CRDP)机制，UH CRC计划基金已承诺支持多达三名有前途的临床研究人员获得独立研究拨款。这与密歇根大学的整体生物医学研究议程一致，加强了其竞争NIH机构临床翻译科学奖的地位。 与其竞争性续签申请中划定的优先事项一致，夏威夷儿童基金会继续专注于实现其主要目标，即为旨在改善夏威夷不同人群健康和福祉的临床研究提供基础设施支持。该方案的具体目标已作了修改，以反映NIHS对翻译研究的重视，现概述如下： 目标1：继续提供必要的物质和智力基础设施，以支持UH的安全和符合文化要求的临床研究。 目的2：培养和发展训练有素、多产的临床研究队伍。 目标3：建立和完善早期人类发育、生物营养、艾滋病毒和癌症方面的临床卓越和专业知识，特别强调与夏威夷人口临床相关的问题。 目标4：继续在基于社区的参与性研究上合作，并通过拟议的临床翻译科学奖(CTSA)扩大研究合作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The University of Hawaii Clinical Research Center (UH CRC) was established in 1995 through a collaboration between the Pacific Biomedical Research Center (PBRC) and John A. Burns School of Medicine (JABSOM) of the University of Hawaii (UH), and the Kapiolani Medical Center for Women and Children (KMCWC). Since inception of the program, the UH CRC has operated an outpatient research clinic at KMCWC, which has served as its primary base of clinical activity. During the current funding cycle, the UH CRC has been expanded to include a Magnetic Resonance (MR) Core Lab at The Queens Medical Center (QMC), with plans for development of a new outpatient research clinic at QMC currently underway. The program has also expanded to include a HIV research core with the Hawaii AIDS Clinical Research Program (HACRP) at Leahi Hospital, and is pursuing plans to develop a Bionutrition research core at the Kaiser Permanente Center for Health Research Hawaii (CHRH). Lastly, through establishment of the Clinical Research Development Project (CRDP) mechanism, UH CRC program funds have been committed to support up to three promising clinical investigators in their progression towards independent research grants. This is done in congruence with the overall biomedical research agenda of UH, strengthening its position to compete for a NIH institutional Clinical Translational Science Award. In congruence with the priorities delineated in its competitive renewal application, the UH CRC has continued to focus upon achievement of its primary objective  to provide infrastructure support for clinical research designed to improve the health and well-being of Hawaiis diverse population. The specific aims for the program have been modified to reflect the NIHs emphasis on translational research, and are summarized as follows: Aim 1: To continue to provide the necessary physical and intellectual infrastructure to support safe and culturally appropriate clinical research at UH. Aim 2: To cultivate and develop well-trained and productive clinical research faculty. Aim 3: To build and refine clinical excellence and expertise in Early Human Development, Bionutrition, HIV and Cancer, with particular emphasis on issues of clinical relevance to the populations of the State of Hawaii. Aim 4: To continue to partner on community-based participatory research and to expand research collaborations through the proposed Clinical Translational Science Award (CTSA).