The development of a novel transgenic technology

Atazoa有限公司发现，农场动物射精中存在的精子可以被转基因，这种精子被广泛用于繁殖目的。目前，这种基因修饰包括将编码绿色荧光蛋白(GFP)的基因导入精子，这在显微镜下很容易看到。这种蛋白质本身没有治疗价值，但它确实提供了一种简单的方法来测试和改进将基因引入精子所需的技术。它还将使我们能够测试通过这种方法引入精子的基因是否可以通过体外受精遗传，以及遗传效率如何。这种类型的技术具有潜在的巨大价值，因为目前将基因引入较大动物的方法效率很低，成本也很高。这里提出的新技术有望促进转基因动物的繁育，人们已经知道，转基因动物对开发和发现新的治疗方法具有重要价值。

Atazoa Ltd have found that spermatozoa present in farm animal ejaculates, which are widely used for breeding purposes, can be genetically modified. At present this genetic modification consists of introducing a gene into spermatozoa that encodes a green fluorescent protein (GFP), which can be easily seen by microscopy. This protein is of no therapeutic value in itself but it does provide a simple means to test and improve upon the techniques that are required to introduce genes into sperm. It will also allow us to test whether genes that are introduced into sperm by this method can be inherited through in vitro fertilisation and at what efficiency. This type of technology is potentially of great value because current means of introducing genes into larger animals are very inefficient and expensive. The new technology proposed here promises to facilitate the breeding of genetically modified animals, which are already known to be of great value for the development and discovery of new therapeutic treatments.