Multidisciplinary Research Training in Lung Biology

描述（由申请人提供）： 本申请是一项多学科研究培训补助金，以支持肺和重症监护医学部（PCCM）的一项长期计划，该计划将由现任主任Peter瓦格纳博士指导。 它的目的是准备精心挑选的医生科学家实习生的职业生涯在肺生物学，健康和疾病的学术研究，并将支持他们在18个月的研究组成部分，他们的3年奖学金。 与12名研究员在该计划（每年4），我们要求6个博士后职位。 这项建议的核心将继续是受训人员直接参与研究，在经验丰富的基础和临床科学家的指导下，他们在培训过程中有着富有成效的、资助的调查项目和经验。 研究培训机会分为三个重点领域，提供培训和调查的实质性深度- 1）肺血管生物学; 2）气道生物学（每个都提供基础和临床实验室研究）;和3）以患者为导向的研究，后者提供MPH学位选项。 核心教师（20名成员）主要由PCCM司选定的调查人员组成。 一些与PCCM建立联系的核心教师来自其他部门，甚至来自圣地亚哥州立大学。 他们提供了一个强大的多学科组成部分，以资助研究和研究培训和生产力的良好记录的计划。 25名支持教师，谁进一步提高多学科的可能性，是一个组合：1）初级PCCM教师谁将被指导成为未来的核心教师; 2）主要是临床教师谁将提供协作界面的许多病人/疾病，我们的学员将研究; 3）PCCM以外的教师，他们可以支持特定的研究领域和方法，但由于他们的主要任命或研究兴趣，他们也与其他计划有关。 该研究项目将由安迪·里斯博士共同主持的研究培训委员会直接监督， 患者导向研究副主任和基础研究副主任Jason Yuan博士。 一个由Peter Fedullo博士主持的临床培训委员会将协调临床培训（不受此资助），一个由瓦格纳博士主持的执行奖学金委员会（成员里斯、袁和Fedullo）将监督整个三年计划。 特别注意通过正式课程进行合乎道德的研究;指导研究员和初级教员;以及征聘代表性不足的少数民族（2003年四名入学研究员中有一名是非洲裔美国人）。

DESCRIPTION (provided by applicant): This application is for a multidisciplinary research training grant to support a longstanding program in the Pulmonary and Critical Care Medicine Division (PCCM), to be directed by its current Chief, Dr. Peter Wagner. Its purpose is to prepare carefully selected physician scientist trainees for careers in academic research in lung biology, health, and disease and will support them during the 18 months research component of their 3 year fellowship. With 12 fellows in the program (4 per year), we request six postdoctoral positions. The centerpiece of this proposal will continue to be the direct involvement of trainees in research, under the preceptorship of experienced basic and clinical scientists with a record of productive, funded investigative programs and experience in the training process. The research training opportunities are divided into three focus areas that offer substantial depth in training and investigation - 1) pulmonary vascular biology; 2) airway biology (each offering both basic and clinical laboratory research); and 3) patient-oriented research, the latter offering an MPH degree option. The Core faculty (20 members) consists largely of selected investigators from the PCCM Division. Some core faculty with established ties to PCCM come from other Divisions/Depts and even from San Diego State University. They provide a strong multidisciplinary component to the program with funded research and a proven track record of research training and productivity. The 25 Supporting faculty, who further enhance the multidisciplinary possibilities, are a combination of: 1) junior PCCM faculty who will be mentored to become future core faculty; 2) mostly clinical faculty who will provide the collaborative interface to many of the patients/diseases our trainees will study; and 3) faculty outside PCCM who are available to support particular areas and methods of research, but who, by virtue of their primary appointment or research interest, are also associated with other programs. The research program will be directly overseen by a research training committee cochaired by Dr. Andy Ries, Associate Director for Patient Oriented Research and Dr. Jason Yuan, Associate Director for Basic Research. A clinical training committee chaired by Dr. Peter Fedullo will coordinate clinical training (not supported by this grant), and an executive fellowship committee chaired by Dr. Wagner (members Ries, Yuan and Fedullo) will oversee the entire three year program. Special attention is given to ethical conduct of research through formal coursework; to mentoring fellows and junior faculty; and to recruitment of underrepresented minorities (one of four entering fellows in 2003 is African American).