Postdoctoral Training in Cardiovascular Clinical Research

描述(申请人提供)：这是这项临床心血管T32培训补助金的第一次竞争性续签申请，最初是在2003年资助的。对于这次续签申请，我们根据特别强调小组2002年11月的批评，根据我们对该计划的初步经验，以及过去4年来心血管医学的变化，对我们的计划进行了重大修改。这些计划的变化包括放弃使用培训路径，增加我们的导师教师，以及增强我们的授课课程。该计划的三个目标是为学员提供：1)临床研究方法的教学培训，2)有指导的研究经验，以及3)成功学术生涯所需的“生存技能”的培训和经验。实习生将在这个项目中学习两年。在2003年7月1日至2007年6月30日的资助期内，已有5名学员完成了该方案，3名学员目前正在接受第一年的培训。在完成该项目的5人中，有3人被任命为学术教员(杜克大学2人，埃默里大学1人)。到目前为止，这组受训人员已在同行评审员期刊上发表了16篇第一作者论文，其中4名受训人员已申请并获得了校外研究经费。对参与计划的导师进行关于良好指导的基本要素的正式培训将继续是我们计划的一个主要特点。跨学科共同指导是我们培训计划的标准。代表杜克大学6个系(内科、外科、麻醉学、儿科、行为医学/精神病学和放射学)的28名教职员工将作为导师参加这个项目。在每个奖学金的过程中，使用几种方法来监测进展，包括受训者和主要导师之间的每周会议，以及每名受训者与计划主任的季度会议。跟踪的成果包括在国家会议上的陈述、同行审查的出版物和至少一次赠款申请。我们正在申请6个博士后级别的实习生名额，这比我们目前每年3个名额的资助水平有所增加。在2006年的申请年度，我们收到500份心血管培训申请，面试了60名应聘者。在这些人中，52人符合培训补助金条件，35人寻求临床研究培训。因此，我们认为，我们拥有足够多的高素质候选人、杰出的导师和丰富多样的临床研究资源，以支持我们项目规模的扩大。

Description (provided by applicant): This is the first competitive renewal application for this clinical cardiovascular T32 training grant, which was initially funded in 2003. For this renewal application, we have made significant changes in our program in response to the Special Emphasis Panel critique of November 2002, in response to our initial experience with the program and in response to changes in cardiovascular medicine over the last 4 years. These program changes include dropping the use of training tracks, additions to our mentor faculty, and enhancements to our didactic course offerings. The 3 objectives of this program are to provide trainees with: 1) didactic training in the methods of clinical research, 2) a mentored research experience, and 3) training and experience in "survival skills" required for a successful academic career. Trainees spend 2 years in this program. During the funding period from 7/1/2003 to 6/30/2007, 5 trainees have completed the program and 3 are currently in the first year of training. Of the 5 who have finished the program, 3 have academic faculty appointments (2 at Duke, 1 at Emory). To date, this group of trainees has produced 16 first author publications in peer-reviewer journals and 4 of the trainees have applied for and been awarded extramural research funding. Formal training of participating mentors on the essentials of good mentoring will continue to be a major feature of our program. Interdisciplinary co-mentoring is standard in our training program. Twenty-eight faculty members representing 6 departments at Duke (Medicine, Surgery, Anesthesiology, Pediatrics, Behavioral Medicine/Psychiatry and Radiology) will participate as mentors in this program. During the course of each fellowship, several methods are used to monitor progress, including weekly meetings between the trainee and the primary mentor, and quarterly meetings for each trainee with the Program Director. Outcomes tracked include presentations at national meetings, peer-reviewed publications, and at least one grant application. We are requesting 6 trainee slots at the post-doctoral level, an increase from our currently funded level of 3 slots per year. In the application year 2006, we received 500 applications for Cardiovascular Training and interviewed 60 candidates. Of these, 52 were training grant eligible and 35 were seeking training in clinical research. We therefore feel that we have the critical mass of high quality candidates, outstanding mentors and a rich diversity of clinical research resources to support an increase in the size of our program.