Academic Training in Rheumatology

描述(由申请人提供)：医学面临的最大挑战是将当代科学的最新发展带到床边。只有培养一支能够进行高质量研究的调查队伍，以加强以患者为导向的调查，才能应对这一挑战。因此，这项培训拨款建议寻求支持，使个人(医学博士、医学博士或博士)为从事与风湿病相关的生物医学科学做好准备。该项目的基础是一个庞大的风湿科，拥有30名教职员工，其中包括14名联邦资助的研究人员，以及活跃的临床和基础研究项目。风湿科，包括其相关的诊所，是加州大学洛杉矶分校大卫·格芬医学院的一部分，设有临床和生物医学科学系。主要的教师顾问不仅来自医学系内部的部门，而且还来自病理学系、微生物/免疫学/分子生物学。遗传学、药理学和公共卫生学院。涵盖的专业领域广泛，包括自身免疫、基础免疫学、临床干预和治疗、基因组学、基因表达和治疗，以及卫生质量、经济和政策。该计划得到了核心设施的良好支持，以及由PI发起的学术课程和全校范围的翻译免疫学计划。据信，这个风湿病项目提供了独特的资源，并将继续扩大对研究有职业兴趣的个人池，因为它与子专业有关，随着分子医学在临床上的应用越来越多，这个池太小了，无法满足未来几十年的要求。 奖学金计划的第一年包括广泛的临床培训，资金来自当地来源。在第二年和第三年，学员将在他/她选择的研究领域工作，同时保持足够的临床活动，以满足专业委员会的要求。希望和/或需要经验以过渡到学术研究人员的受训者将通过拟议的T32计划获得资助，对于那些选择博士或硕士课程的受训者，将通过加州大学洛杉矶分校的STAR(高级研究专业培训)计划获得资助。本申请寻求对关键的两年期间的支持，这段时间是实习生从她/他最初的风湿病临床经验过渡到学术风湿病职业生涯的关键时期。该申请还寻求为希望接受风湿病学培训以发展子专业学术研究生涯的非临床博士后学员提供为期两年的培训支持。

DESCRIPTION (provided by applicant): The greatest challenge to medicine is to bring to the bedside the latest developments in contemporary science. This challenge can only be met by developing a cadre of investigators who can conduct high quality research that is geared to strengthen patient-oriented investigations. Hence, this training grant proposal seeks support to prepare individuals (MD, MD/PhD, or PhD) for a career in biomedical science as it relates to Rheumatology. The program is based in a large Division of Rheumatology with 30 faculty members including 14 federally funded investigators and active clinical and basic research programs. The Division of Rheumatology, including its related clinics, is part of the David Geffen School of Medicine at UCLA with its clinical and biomedical science departments. The primary faculty advisors come not only from divisions within the Department of Medicine but also from the Departments of Pathology, Microbiol/lmmunol /Mol. Genetics, Pharmacology, and School of Public Health. The broad areas of expertise covered include autoimmunity, basic immunology, clinical intervention and therapeutics, genomics, gene expression and therapy, and health quality, economics and policy. The program is well supported by core facilities as well as by academic courses and a campus-wide translational immunology program initiated by the PI. It is believed that this Rheumatology program provides unique resources and will continue to enlarge the pool of individuals with a career interest in research as it relates to the subspecialty, a pool that is far too small to meet the requirements of the next decades as molecular medicine is increasingly applied in the clinic. The first year of the fellowship program consists of extensive clinical training and is funded through local sources. During the 2nd and 3rd years, the trainee will work in his/her chosen area of research, while maintaining sufficient clinical activity to fulfill the specialty board requirements. The trainees desiring and/or requiring experience to make the transition to academic investigator will be funded through the proposed T32 and for those who elect PhD or Master's curricula, through the UCLA STAR (Specialty Training in Advanced Research) program. This application seeks support for the critical 2-year period which transitions the trainee from her/his initial clinical rheumatology experience to a career in academic rheumatology. The application also seeks two-year training support for non-clinical postdoctoral trainees who desire to train in Rheumatology to develop an academic research career in the subspecialty.