Scientist Training in Rheumatology Research
Scientist Training in Rheumatology Research
批准号:
10851080
负责人:
Jason Knight
金额:
$16.94万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-09-12 至 2028-06-30
中文摘要
项目摘要/摘要
本申请是密歇根大学科学家项目的行政补充申请
风湿病研究培训(T32AR007080)。我们的计划,自1975年以来由NIAMS资助,是
旨在培养杰出的博士后科学家,包括医学博士和博士,以从事研究工作
与风湿病相关的研究。我们的计划是由几个关键因素推动的,包括(I)
风湿病的无情负担造成的巨大临床需求;(Ii)认识到
风湿性疾病是由需要多学科方法的复杂过程推动的;以及
受到威胁的不同研究人员致力于风湿病研究的职业
研究。这一行政补充的短期目标是提供更多的机会
培训的重点是研究疼痛的机制、测量和治疗
现有的NIAMS T32培训计划。长期目标是发展一支多元化的研究队伍
它具有解决这些领域现有差距所需的技能和内容专门知识。
目标1的目标是开发新的、可扩展的教育活动,使受训者(内部和
外部)获得必要的知识和经验,以便将疼痛研究纳入他们的研究
事业。具体地说,由大卫·威廉姆斯博士(联系国家医疗K12计划的PI)领导的一个小组将
将他们在密歇根大学非常成功的课程:疼痛入门:机制,测量,
和治疗,纳入一个在线课程,旨在跟上不断变化的临床疼痛领域的步伐
研究。该1.0版将成为加州大学K和T32疼痛学者的基础课程
密歇根州以及全国通过积极联合疼痛研究人员来评论、合成和
建立(目的)关系网。
目标2的目标是在我们现有的计划中增加一名实习生。我们已经确认了一名非常合格的
候选人雅各布·戴博士,他将开始与我们现有的导师之一丹尼尔·克劳夫博士一起培训。在
我们计划的范围,Aday博士和Clauw博士构思了一个创新的项目,围绕着
迷幻辅助治疗纤维肌痛的前沿临床试验。Aday博士致力于寻求一种
NIAMS使命下的疼痛研究人员的职业生涯,并制定了体验式学习计划,
课程和指导,这些都是他实现及时目标所必需的。
英文摘要
PROJECT SUMMARY/ABSTRACT
This application is for an administrative supplement to the University of Michigan's Program for Scientist
Training in Rheumatology Research (T32AR007080). Our Program, funded by NIAMS since 1975, is
designed to prepare outstanding postdoctoral scientists, both MD and PhD, for investigative careers in
research related to rheumatic diseases. Our Program is motivated by several key factors including (i) the
tremendous clinical need caused by the unrelenting burden of rheumatic diseases; (ii) an appreciation that
rheumatic diseases are propelled by complex processes in need of multidisciplinary approaches; and (iii) a
threatened pipeline of diverse investigators committed to careers that will be devoted to rheumatology
research. The short-term goal of this administrative supplement is to provide increased opportunities
for training focused on the study of the mechanisms, measurement, and treatment of pain within our
existing NIAMS T32 Training Program. The long-term goal is to develop a diverse research workforce
that has the skills and content expertise needed to address the existing gaps in these areas.
The goal of Aim 1 is to develop new, scalable educational activities that will allow trainees (both internal and
external) to gain the knowledge and experience necessary to integrate the study of pain into their research
careers. Specifically, a team led by Dr. David Williams (contact PI for the National HEAL K12 Program) will
convert their highly successful University of Michigan course, Introduction to Pain: Mechanisms, Measurement,
and Treatment, into an online curriculum designed to keep pace with the everchanging field of clinical pain
research. This version 1.0 will be the foundational curriculum for K and T32 pain scholars at the University of
Michigan, as well as nationally through the Positively Uniting Researchers of Pain to Opine, Synthesize, &
Engage (PURPOSE) network.
The goal of Aim 2 is to add an additional trainee to our existing Program. We have identified a highly qualified
candidate, Dr. Jacob Aday, who will begin training with one of our existing mentors, Dr. Daniel Clauw. Within
the scope of our Program, Drs. Aday and Clauw have conceived an innovative project developed around a
cutting-edge clinical trial of psychedelic-assisted therapy for fibromyalgia. Dr. Aday is committed to pursuing a
career as a pain researcher under the NIAMS mission and has developed a plan for the experiential learning,
coursework, and mentorship that are necessary for him to achieve his timely goal.
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Breast calcinosis in a patient with Dermatomyositis.
皮肌炎患者的乳房钙质沉着。
DOI:
10.5152/eurjrheum.2016.15080
发表时间:
2017
期刊:
European journal of rheumatology
影响因子:
1.9
作者:
[Namas,Rajaie, Beydoun,Nassar, Meysami,Alireza]
通讯作者:
Meysami,Alireza
DOI:
10.1002/art.40372
发表时间:
2018-03
期刊:
Arthritis & rheumatology (Hoboken, N.J.)
影响因子:
--
作者:
[Irizarry-Caro JA, Carmona-Rivera C, Schwartz DM, Khaznadar SS, Kaplan MJ, Grayson PC]
通讯作者:
Grayson PC
DOI:
10.3389/fimmu.2018.01680
发表时间:
2018
期刊:
Frontiers in immunology
影响因子:
7.3
作者:
[Liu Y, Carmona-Rivera C, Moore E, Seto NL, Knight JS, Pryor M, Yang ZH, Hemmers S, Remaley AT, Mowen KA, Kaplan MJ]
通讯作者:
Kaplan MJ
Fucosyltransferase 1 mediates angiogenesis in rheumatoid arthritis.
岩藻糖基转移酶1介导类风湿关节炎中的血管生成。
DOI:
10.1002/art.38648
发表时间:
2014-08
期刊:
ARTHRITIS & RHEUMATOLOGY
影响因子:
13.3
作者:
[Isozaki, Takeo, Amin, Mohammad A., Ruth, Jeffrey H., Campbell, Phillip L., Tsou, Pei-Suen, Ha, Christine M., Stinson, W. Alex, Domino, Steven E., Koch, Alisa E.]
通讯作者:
Koch, Alisa E.
DOI:
10.1136/annrheumdis-2018-213746
发表时间:
2018-12
期刊:
Annals of the rheumatic diseases
影响因子:
27.4
作者:
[Mistry P, Carmona-Rivera C, Ombrello AK, Hoffmann P, Seto NL, Jones A, Stone DL, Naz F, Carlucci P, Dell'Orso S, Gutierrez-Cruz G, Sun HW, Kastner DL, Aksentijevich I, Kaplan MJ]
通讯作者:
Kaplan MJ
共 15 条
NETs as therapeutic targets in obstetric APS
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批准号:10786977
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项目类别:
-
资助金额:$42.9万
-
财政年份:2023
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负责人:Jason Knight
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依托单位:
Purinergic modulation of the autoimmune vascular phenotype
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批准号:10364621
-
项目类别:
-
资助金额:$56.76万
-
财政年份:2018
-
负责人:Jason Knight
-
依托单位:
Purinergic modulation of the autoimmune vascular phenotype
-
批准号:10168724
-
项目类别:
-
资助金额:$15.6万
-
财政年份:2018
-
负责人:Jason Knight
-
依托单位:
Purinergic modulation of the autoimmune vascular phenotype
-
批准号:10581346
-
项目类别:
-
资助金额:$36.12万
-
财政年份:2018
-
负责人:Jason Knight
-
依托单位:
Innate Immunity in the Pathogenesis of Lupus and Antiphospholipid Vasculopathy
-
批准号:9392606
-
项目类别:
-
资助金额:$0.09万
-
财政年份:2014
-
负责人:Jason Knight
-
依托单位:
Innate Immunity in the Pathogenesis of Lupus and Antiphospholipid Vasculopathy
-
批准号:8751822
-
项目类别:
-
资助金额:$12.84万
-
财政年份:2014
-
负责人:Jason Knight
-
依托单位:
Training of Arthritis Research Scientists
-
批准号:10214517
-
项目类别:
-
资助金额:$29.67万
-
财政年份:1976
-
负责人:Jason Knight
-
依托单位:
Scientist Training in Rheumatology Research
-
批准号:10627099
-
项目类别:
-
资助金额:$35.34万
-
财政年份:1976
-
负责人:Jason Knight
-
依托单位:
Training of Arthritis Research Scientists
-
批准号:10463710
-
项目类别:
-
资助金额:$30.31万
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财政年份:1976
-
负责人:Jason Knight
-
依托单位:
海外基金