Plasmid Biology 2008 Symposium

描述（由申请人提供）： 本提案寻求资金，以支持将于2008年8月30日至9月5日在波兰的格但斯克举行的国际质粒生物学会议（质粒生物学2008）。本次会议的目的是汇集科学家在质粒生物学的所有领域工作，讨论该领域的最新进展。质体是在原核生物、真核生物和古生物中发现的一组独特的遗传元件。它们是细菌遗传多样性的主要来源，并负责自然界中各种基因的传播，包括编码抗生素抗性、毒素和参与细菌毒力的基因。质粒还用作基础生物学研究的模型，例如复制、基因表达和重组等。塑料也是与医学/兽医学、基因组学、生物技术、农业和环境有关的行业的重要工具。为了更好地理解质粒在自然界中持久存在和传播的分子机制，有必要对质粒生物学进行积极的研究。2008年质粒生物学代表了每两年举行一次的专题讨论会的延续，讨论该领域每两年的重大进展。会议将讨论质粒生物学的各个方面，如它们的复制，分配/稳定性，转移，基因组学，进化，生态学，它们作为水平基因库来源的作用，包括抗生素抗性和毒力基因，参与细菌毒力，医学和兽医方面，应用方面和生物信息学。我们预计将有大约150-200名科学家出席，其中大约一半来自美国，一半来自世界其他地区。目前还没有类似的国际会议涵盖质粒生物学的所有领域。本次会议服务于国际质粒生物学社区，并为交流对该领域持续进步至关重要的思想提供了一个极好的论坛。过去会议的与会者包括该领域的领导人以及年轻科学家、研究生、博士后研究员和少数民族科学家。会议将包括应邀发言者以及根据提交的摘要选定的发言者。NIH的资金被要求支持10名美国人的旅行费用，其中至少5人将是博士前/博士后学员或少数民族科学家。美国国立卫生研究院的资金也被要求支持10个额外的美国个人的注册/住宿费用，其中至少5人将是博士前/博士后学员或少数民族科学家。因此，我们计划为总共20名美国科学家提供部分支持，为10名个人提供旅行支持，并为另外10名个人提供注册/住宿费用。本提案寻求资金，以支持将于2008年8月30日至9月5日在波兰的格但斯克举行的国际质粒生物学会议（质粒生物学2008）。本次会议的目的是汇集科学家在质粒生物学的所有领域工作，讨论该领域的最新进展。质粒是细菌遗传多样性的主要来源，并负责自然界中各种基因的传播，包括编码抗生素抗性、毒素和参与细菌毒力的基因。在与医药、兽医学、基因组学、生物技术、农业和环境有关的行业中，质粒也是重要的工具。

DESCRIPTION (provided by applicant): This proposal seeks funds to support the International Plasmid Biology Conference (Plasmid Biology 2008) to be held in Gdansk, Poland from August 30th to September 5th 2008. The goals of this meeting are to bring together scientists working in all the areas of plasmid biology to discuss the latest advances in the field. Plasmids represent a unique group of genetic elements found in prokaryotes, eukaryotes and archaeon. They are a major source of genetic diversity in bacteria and are responsible for the spread of a variety of genes in nature, including those encoding antibiotic resistance, toxins and those involved in bacterial virulence. Plasmids also serve as models for basic biological studies such as replication, gene expression, and recombination, to name a few. Plasmids are also important tools in industries related to medicine/veterinary medicine, genomics, biotechnology, agriculture and environment. Vigorous studies on plasmid biology are necessary for a better understanding of the molecular mechanisms involved in their persistence and spread in nature. Plasmid Biology 2008 represents a continuation of the bi-annual symposia held to discuss the highlights of major advances in this field every two years. The meeting will include a discussion of all aspects of plasmid biology such as their replication, partition/stability, transfer, genomics, evolution, ecology, their role as a source of horizontal gene pool, including antibiotic resistance and virulence genes, involvement in bacterial virulence, medical and veterinary aspects, applied aspects, and bioinformatics. We anticipate attendance by approximately 150-200 scientists, approximately one-half from the United States and one-half from the rest of the world. There is no similar international meeting that covers all the areas of plasmid biology. This meeting serves the international plasmid biology community and provides an excellent forum for exchange of ideas that are critical for the continued advances in the field. Participants in the past meeting have included leaders in the field as well as younger scientists, graduate students, postdoctoral fellows and minority scientists. The meeting will include invited speakers as well as speakers selected on the basis of submitted abstracts. NIH funds are requested to support the travel expenses of 10 US individuals, at least 5 of which will be predoctoral/postdoctoral trainees or minority scientists. NIH funds are also requested to support the registration/lodging expenses of 10 additional US individuals, at least 5 of which will be predoctoral/postdoctoral trainees or minority scientists. Thus, we plan to provide partial support for a total of 20 US scientists, providing travel support for 10 individuals and registration/lodging expenses for another 10 individuals. This proposal seeks funds to support the International Plasmid Biology Conference (Plasmid Biology 2008) to be held in Gdansk, Poland from August 30th to September 5th 2008. The goals of this meeting are to bring together scientists working in all the areas of plasmid biology to discuss the latest advances in the field. Plasmids are a major source of genetic diversity in bacteria and are responsible for the spread of a variety of genes in nature, including those encoding antibiotic resistance, toxins and those involved in bacterial virulence. Plasmids are also important tools in industries related to medicine, veterinary medicine, genomics, biotechnology, agriculture and environment.