AOSSM Post-Joint Injury Osteoarthritis Conference

描述(由申请人提供)：骨关节炎(OA)是最常见的关节疾病，也是全球残疾的主要原因[1，2]。单个下肢关节骨关节炎造成的身体损害相当于报道的主要改变生活的疾病，如终末期肾脏疾病和心力衰竭。骨性关节炎的病因还不是很清楚。[3]然而，关节创伤是主要的病因[1，2，4]。与那些没有关节损伤的患者相比，遭受膝关节韧带和半月板损伤的患者发生骨性关节炎的风险增加10倍[7，8]。在前十字韧带撕裂12年后，82%的女足球运动员在膝关节X光片上出现了病变，75%的女足球运动员在平均年龄仅31岁时出现了影响与膝盖相关的生活质量的症状[9，10]。伴随的半月板损伤与膝骨性关节炎的发病率更高有关。前交叉韧带和半月板损伤是骨科医生治疗的最常见的关节损伤。美国运动医学整形外科学会(AOSSM)是致力于运动医学的整形外科医生的全国性组织，专注于治疗活跃的个人通常遭受的伤害。AOSSM成立于1972年，最初是一个教育和研究论坛，现在是运动医学教育、研究、交流和奖学金方面的世界领先者。目前AOSSM的一个战略重点是评估支持和提高运动医学研究质量的方法，方法是确定关键的研究领域，并召集研究人员与临床医生交换信息并制定研究重点。这次会议的目的是召集该领域的领导者，探讨关节损伤与骨性关节炎发展之间的密切联系。临床领导者和基础科学家将聚集在一起，确定当前和新兴的研究领域，就合作研究新领域的未来方向达成共识，并制定新的合作和战略，将基础研究转化为患者护理。AOSSM关节损伤后骨关节炎研讨会将于2008年12月11日至14日在洛杉矶新奥尔良一家交通便利的酒店和会议中心举行。每一次会议将由一名AOSSM临床医生兼科学家和一名在会议主题方面具有专业知识的科学家主持。组织者和教职员工是一个多元化的群体，既有男性也有女性，来自美国不同地区和国外。其他参与者将包括10名青年调查员(YI)、14名普通参与者、5名工业界代表和5名来自美国国立卫生研究院的代表。YI计划将放弃多达10名住院医生/科学家参加的机会。彝族申请者必须在42岁以下或培训后8年内。研讨会的结果将通过发表在AOSSM专著《美国运动医学杂志》上向肌肉骨骼界传播，也将在AOSSM网站上向公众免费提供。关节受伤的人在年富力强的时候患上致残性磨损骨关节炎的风险很高。这次研讨会将把医生和科学家聚集在一起，制定研究计划，寻找防止这种情况发生的新方法。

DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the most common joint disease and is a leading cause of disability worldwide [1,2] . The physical impairment from OA of a single lower extremity joint is equivalent to that reported for major life-altering disorders such as end-stage kidney disease and heart failure. The causes of OA are not well understood. [3] However, joint trauma is a leading etiological factor [1,2,4] . Patients sustaining ligament and meniscal injuries of the knee have a ten-fold increased risk of OA when compared to those who did not have a joint injury [7,8] . Twelve years after an anterior cruciate ligament tear, 82% of female soccer players had pathological changes on knee radiographs and 75% had symptoms affecting their knee related quality of life at an average age of just 31 years old [9,10] . Concomitant meniscal injury is associated with an even higher prevalence of knee OA. ACL and meniscal injuries are the most common joint injuries treated by orthopaedic surgeons. The American Orthopaedic Society for Sports Medicine (AOSSM) is a national organization of orthopaedic surgeons dedicated to sports medicine and focuses on the treatment of injuries commonly sustained by active individuals. Formed in 1972 primarily as a forum for education and research, the AOSSM is now a world leader in sports medicine education, research, communication, and fellowship. A current AOSSM strategic priority is to evaluate methods to support and improve the quality of sports medicine research by identifying critical areas for study and by convening researchers with clinicians to exchange information and develop research priorities. The purpose of this conference is to convene leaders in the field to explore the strong association between joint injury and the development of osteoarthritis. Both clinical leaders and basic scientists will be brought together to determine the current and emerging areas of research, to develop a consensus on future directions in new areas of cooperative research, and to develop new collaborations and strategies for the translation of basic research into patient care. The AOSSM Post-joint Injury Osteoarthritis symposium will be December 11-14, 2008 in New Orleans, LA at a fully-accessible hotel and meeting center. Each session will be moderated by an AOSSM clinician-scientist, and a scientist with expertise in the session topic. The organizers and the faculty are a diverse group, both men and women, from the different parts of the US and abroad. Other participants will include 10 Young Investigators (YI), 14 at-large participants, 5 representatives from industry, and 5 representatives from the NIH. The YI Program will give up to 10 residents/scientists the opportunity to attend. YI applicants must be under 42 years of age or less than 8 years beyond training. The results of the symposium will be disseminated to the musculoskeletal community through publication in the American Journal of Sports Medicine an AOSSM monograph and will also be freely available to the public on the AOSSM website. People suffering injuries to their joints are at high risk of developing disabling wear and tear osteoarthritis in the prime of their lives. This symposium will bring doctors and scientists together to develop research plans to find new methods to prevent this from happening.