39th Annual International Narcotics Research Conference

描述(申请人提供)：这笔赠款是为2008年7月7日至11日在南卡罗来纳州查尔斯顿举行的第39届国际麻醉品研究会议(INRC)申请资助。多年来，INRC一直是传播和交流有关阿片类药物和内源性阿片系统生物医学研究信息的最负盛名的国际会议。主题包括从分子到行为和临床研究。虽然主要话题仍然是鸦片类药物和滥用，但对其他滥用药物的讨论越来越多，如大麻、可卡因、苯丙胺和酒精，因为这些药物与内源性阿片系统之间的广泛相互作用已被记录在案。请求提供支助的主要是部分旅费，以使青年科学家，即研究生、博士后研究员和初级教员能够参加会议。被邀请的研讨会演讲者，通常不是INRC的参与者，将得到部分支持。请拨的行政和会议费用约占总额的10%。今年，INRC有三位确认的不同主题的全体演讲者，包括医学大学的Peter Kalivas博士和Gary Aston-Jones博士。南卡罗来纳州的萨姆·戴德威勒博士，来自维克森林大学。来自大学的简·范·瑞博士。荷兰的乌得勒支当选为2008年会议的创始讲师。七个研讨会将涵盖应用中描述的广泛主题，包括药物寻找、奖励系统的阿片调节、药物滥用中的遗传学和基因组学、阿片受体调节和信号、抑郁症和阿片类药物的翻译研究、KOR系统中的分子调节失调以及体内阿片成像。在每一次研讨会上，将选出一些相关的来稿进行口头陈述。将有三个海报会议，在那里总是有很多交流和讨论。将有一个NIDA研讨会，重点是关于分子图书馆筛选中心网络(MLSCN)的NIH路线图倡议。对于来自许多国家的与会者来说，这次国际会议是他们见面和交流思想的唯一机会。我们认为，许多博士后和博士后实习生的参与已经导致并可能继续导致招募有前途的科学家从事药物滥用研究。公共卫生相关性：吸毒成瘾是一个日益严重的健康问题。第39届国际麻醉品研究会议为毒品滥用研究领域的研究人员提供了一个机会，就这一重要研究领域的最新发展进行会面和交流。

DESCRIPTION (provided by applicant): This grant is to request support for the 39th annual meeting of the International Narcotics Research Conference (INRC) to be held in Charleston, South Carolina from July 7-11, 2008. INRC has been for many years the most prestigious international meeting for the dissemination and exchange of information about biomedical research on opiate drugs and the endogenous opioid system. The topics range from molecular to behavioral and clinical studies. While the main topic is still opiate drugs and abuse, there is increasing discussion of other abused drugs, such as marijuana, cocaine, amphetamines, and alcohol, since extensive interactions have been documented between these drugs and the endogenous opioid system. Support is requested primarily for partial travel support to enable young scientists, i.e. graduate students, postdoctoral fellows, and junior faculty, to participate in the Conference. Invited symposium speakers, not normally INRC participants, will receive partial support. Funds requested for administrative and meeting expenses represent ~10% of the total. This year, INRC has three confirmed plenary speakers on various topics, including Drs. Peter Kalivas and Gary Aston-Jones, Medical Univ. of South Carolina, Dr. Sam Deadwyler, Wake Forest University. Dr. Jan van Ree from the Univ. of Utrecht, Netherlands was elected the Founders' Lecturer for the 2008 Meeting. Seven symposia will cover a wide range of topics as described in the application, including drug seeking, opioid regulation of reward system, genetics and genomics in drug abuse, opioid receptor regulation and signaling, translational studies in depression and opioids, molecular dysregulation in the KOR system and in vivo opioid imaging. A number of relevant contributed papers will be chosen for oral presentation at each symposium. There will be three poster sessions, at which there is always much exchange and discussion. There will be a NIDA workshop focusing on the NIH roadmap initiative on the Molecular Libraries Screening Centers Network (MLSCN). For participants from many countries, this international meeting is their only chance to meet and exchange ideas. We feel that participation by many pre- and post- doctoral trainees has resulted and is likely to continue to result in recruiting promising scientists to a career of drug abuse research. PUBLIC HEALTH RELEVANCE: Drug addiction is an increasing health concern. The 39th International Narcotics Research Conference provides an opportunity for investigators in the field of drug abuse research to meet and exchange ideas about the latest developments in this important area of research.