2008 Muscle and Molecular Motors Gordon Research Conference

描述（由申请人提供）：本提案旨在支持将于2008年6月29日至7月4日在美国新罕布什尔州新伦敦举行的“肌肉和分子马达”国际研讨会（戈登研究会议）。该会议每三年举行一次，像许多戈登研究会议一样，是我们研究领域最重要和最负盛名的会议。它提供了一个信息交流的论坛，可以整合有关肌肉和运动蛋白结构和功能，能量转导机制以及分子运动在疾病和人类健康中的作用的知识。定向运动是所有生物体的基本特征，分子马达是通过将化学势能转化为机械功来驱动这些运动的蛋白质机器。它们执行高度多样化的生物学功能，包括肌肉收缩、细胞分裂、细胞内运输，并在听力和发育生物学中发挥关键作用。它们还能使寄生虫和细菌侵入人类宿主细胞。这次会议的主要目的是增加我们对分子马达的基本机制和功能的了解。

DESCRIPTION (provided by applicant): The aim of this proposal is to help support an international symposium (Gordon Research Conference) on "Muscle and Molecular Motors" to be held between June 29th to July 4th, 2008 in New London, NH, USA. The conference is held every three years and like many Gordon Research Conferences, is the most important and prestigious meeting for our field of research. It provides a forum for information exchange that leads to integration of knowledge about muscle and motor protein structure and function, the mechanism of energy transduction and the role of molecular motors in disease and human health. Directed movement is a fundamental characteristic of all living organisms and molecular motors are the protein machines that drive these movements by converting chemical potential energy into mechanical work. They perform highly diverse biological functions including muscle contraction, cell division, intra-cellular trafficking and have critical roles in hearing and developmental biology. They also enable parasites and bacteria to invade human host cells. The principal aim of this conference is to increase our understanding of the basic mechanism and function of molecular motors.