Environmental Bioinorganic Chemistry 2008 Gordon Research Conference

描述(由申请人提供) 该提案要求部分支持将于2008年6月15-20日在密西西比州沃特维尔山谷举行的第四届戈登环境生物无机化学研究会议(EBIC 2008)。这次会议的广泛和长期目标是在从分子到全球的尺度上了解历史上被称为“无机元素”的元素在生物过程中的作用。技术挑战将使研究人员忽略生命系统不仅仅由碳、氢、氮、磷和氧组成，但他们现在知道，生物圈依赖于或可能容易受到元素周期表的更大部分的影响。此外，虽然人类对某些无机元素的使用由来已久，但现代工业和农业已经导致人类及其环境前所未有地暴露在有毒元素和放射性核素中，对公众健康造成了代价高昂的后果。研究人员的具体目标是在一个可爱的自然环境中与36名演讲者/讨论负责人举行为期5天的会议，他们研究生物组织(从分子到生态系统)的不同规模的生物无机化学，并使用不同的视角和工具。EBIC 2008将以我们主题的蜂窝和全球层面的两个主旨演讲开始。将有七个会议，涉及铁和硫，痕量金属，矿物营养和动态平衡，进化的无机方面，毒理学和生物修复，生物能源和纳米技术，以及生物无机分析的最新进展。两次餐前海报会议(每次两天)将为所有注册者提供相互讨论他们的科学的机会。会议结束时将纪念一位对生物无机化学具有开创性贡献的人。这次会议的意义在于，尽管其他会议侧重于分子和细胞层面的矿物生物学或将生物无机专题列入其环境重点，但EBIC的独特之处在于故意将这些不同的观点结合在一起，以建立跨越空间和时间尺度的生物无机过程之间的联系，并促进发现整个元素周期表中此类过程中的共同和不同模式。2008年EBIC大会与健康相关的是，人类和动物的健康以及慢性病和传染病的防御都依赖于足够的矿物质营养，而矿物质营养是通过植物和微生物直接从土壤和水中获取无机元素来实现的。此外，现代农业、制造业、临床和军事实践大大增加了我们对有毒元素的暴露，这就需要了解和监测它们的风险，并制定战略来防范它们。2008年EBIC大会与健康相关的是，人类和动物的健康以及慢性病和传染病的防御都依赖于足够的矿物质营养，而矿物质营养是通过植物和微生物直接从土壤和水中获取无机元素来实现的。此外，现代农业、制造业、临床和军事实践大大增加了我们对有毒元素的暴露，这就需要了解和监测它们的风险，并制定战略来防范它们。

DESCRIPTION (provided by applicant) This proposal requests partial support for the 4th Gordon Research Conference on Environmental Bioinorganic Chemistry (EBIC 2008) to be held in Waterville Valley, NH, 15-20 June 2008. The broad and long term goal for this conference is to understand the roles in biotic processes of elements historically called "inorganic" at scales from the molecular to the global. Technical challenges will allow the investigators to overlook that living systems consist of more than carbon, hydrogen, nitrogen, phosphorus, and oxygen, but they now know that the biosphere depends on, or can be vulnerable to, a much larger portion of the Periodic Table. Moreover, while human use of some inorganic elements is ancient, modern industry and agriculture have led to unprecedented exposures of humans and their environment to toxic elements and radionuclides with costly consequences for public health. The investigators aim specifically to convene for 5 days in a lovely natural setting with 36 speakers/ discussion leaders who study bioinorganic chemistry at different scales of biological organization (molecular to ecosystem) and with diverse perspectives and tools. EBIC 2008 will open with two keynote addresses on the cellular and global dimensions of our subject. There will be seven sessions covering iron and sulfur, trace metals, mineral nutrition and homeostasis, inorganic aspects of evolution, toxicology and bioremediation, bioenergy and nanotechnology, and recent advances in bioinorganic analysis. Two pre-dinner poster sessions (2-days each) will afford all registrants the opportunity to discuss their science with each other. The conference will close with a remembrance of a seminal contributor to bioinorganic chemistry. The significance of this conference is that while other meetings focus on metallobiology at the molecular and cellular levels or include bioinorganic topics in their environmental focus, EBIC has been unique in deliberately bringing these distinct perspectives together to make connections among bioinorganic processes across spatial and temporal scales and to foster discovery of common and disparate patterns in such processes across the Periodic Table. The health relatedness of the EBIC 2008 conference is that human and animal health and both chronic disorders and defense against infectious diseases depend on adequate mineral nutrition, made possible by plant and microbial acquisition of inorganic elements directly from soil and water. In addition, modern farming, manufacturing, clinical, and military practices have substantially increased our exposure to toxic elements generating a need to understand and monitor their risks and devise strategies to protect against them. The health relatedness of the EBIC 2008 conference is that human and animal health and both chronic disorders and defense against infectious diseases depend on adequate mineral nutrition, made possible by plant and microbial acquisition of inorganic elements directly from soil and water. In addition, modern farming, manufacturing, clinical, and military practices have substantially increased our exposure to toxic elements generating a need to understand and monitor their risks and devise strategies to protect against them.