Pediatric Rheumatology Research Scientific Meeting

描述(由申请者提供)：儿科风湿病研究年度科学会议将是儿科风湿病社区分享最先进的科学方法、科学机会和新技术的论坛。这项提议是我们以前为支持2009年、2010年和2011年会议而提供的会议赠款的延续。这些会议将由儿童关节炎和风湿病研究联盟(CARA)共同主办，该联盟是一个研究网络，由美国和加拿大的大多数儿科风湿病专家组成。这些会议预计为期两天半，将邀请CARA的所有成员、儿科风湿病社区、对儿科风湿病研究感兴趣的个人以及相关领域(内科风湿学、免疫学、流行病学和其他儿科研究网络)的特邀演讲者和专家参加。2009年和2011年的会议将包括一个为期一天的研讨会，名为临床研究要点，然后是一天半的科学会议。为期一天的研讨会将提供关于治疗医生和PI之间的紧张关系、IRB的作用、同意书和同意程序、不良事件报告、优化研究启动、招募和保留、研究监测、现场责任、研究药物处理、方案审查以及现场预算和合同的授课和互动课程。2010年的会议将是两天半的科学会议，将有更多的时间在每个主要疾病领域制定方案。所有会议都将有关于儿童风湿病和临床研究方法的翻译主题的教学会议，以及制定方案的时间。促进的互动会议将确定每个主要疾病领域的关键研究需求和机会，并将未来发展的科学优先事项纳入具体的研究项目。将确定和促进合作机会和指导关系，并将结合临床研究问题确定转化性研究机会。本次会议的目标是：1)了解儿科风湿病的发病机制(免疫、遗传和炎症)、流行病学以及当前和创新的治疗方法方面的最新进展；2)为儿科风湿病研究界提供一个发展合作和指导的论坛；以及3)在与儿科风湿病临床研究相关的主要领域提供培训和教育。这次会议将是CARA实现其主要使命的主要途径之一，即促进高质量研究的发展，并最终创建一个研究组合，其中包括每种类型的儿科风湿病的相关研究项目。儿科风湿学研究年度科学会议是促进和促进儿科风湿病研究的关键，因为儿科风湿学绝对需要合作和科学交流。儿童风湿性疾病家族(包括幼年特发性关节炎、系统性红斑狼疮、幼年皮肌炎、硬皮病和血管炎)是最常见的儿童慢性病，其发病率与青少年1型糖尿病相似。这次会议是美国和加拿大儿科风湿病学的主要场所，旨在确定重要的研究问题，并开发高质量、精心设计的研究来回答这些问题，并最终改善受儿科风湿病影响的儿童的健康状况。

DESCRIPTION (provided by applicant): The Pediatric Rheumatology Research Annual Scientific Meeting will be the forum for the pediatric rheumatology community for sharing the scientific state-of-the-art methodologies, scientific opportunities and new technologies. This proposal is a renewal of our previous conference grant to support meetings in 2009, 2010 and 2011. These meeting will be co-sponsored by the Childhood Arthritis and Rheumatology Research Alliance (CARRA), a research network comprising the majority of pediatric rheumatologists in the US and Canada. These meetings are conceived to be 2 1/2 days and all members of CARRA, the pediatric rheumatology community, individuals interested in pediatric rheumatic disease research will be invited to attend as well as invited speakers and experts in related fields (internal medicine rheumatology, immunology, epidemiology, and other pediatric research networks). The 2009 and 2011 meetings will include a one day workshop called Essentials of Clinical Research followed by 1 & 1/2 day scientific meeting.. The one day workshop will offer a mix of didactic and interactive sessions on the tension between being a treating physician and PI, role of the IRB, consent forms and consenting process, adverse event reporting, optimizing study start up, recruitment and retention, monitoring of studies, site responsibilities, investigational drug handling, protocol review, and site budgeting and contracts. The 2010 meeting will be a 2 & 1/2 day scientific meeting with more time for protocol development in each major disease area. All meetings will have a mix of didactic sessions on translational topics relevant to pediatric rheumatologic diseases and clinical research methodology, and time for development of protocols. Facilitated interactive sessions will identify the key research needs and opportunities in each of the major disease area, with development of the scientific priorities for future development into specific research projects. Collaborative opportunities and mentoring relationships will be identified and fostered, and translational research opportunities will be identified in coordination with clinical research questions. The objectives of this meeting are to: 1) Update the progress in understanding the pathogenesis (immune, genetic, and inflammatory), epidemiology, and current and innovative therapeutic approaches in pediatric rheumatic diseases; 2) Provide a forum for development of collaborations and mentoring for the pediatric rheumatology research community; and 3) Provide training and education in major areas relevant to clinical pediatric rheumatology research. This meeting will be one of the major avenues whereby CARRA will achieve its primary mission of facilitating the development of high-quality research studies and ultimately creating a research portfolio that includes relevant research projects in every type of pediatric rheumatic disease. The Pediatric Rheumatology Research Annual Scientific Meeting is key to fostering and facilitating research in pediatric rheumatic diseases because of the absolute need for collaboration and scientific cross-fertilization in pediatric rheumatology. The family of pediatric rheumatic diseases (including juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, scleroderma, and vasculitis) are among the most common chronic diseases of children comparable in occurrence to juvenile Type 1 Diabetes. This meeting is the major venue in pediatric rheumatology in the US and Canada for identifying the important research questions and developing high-quality, well-conceived studies to answer these questions and ultimately improve the health outcomes of children affected by pediatric rheumatic diseases.