Improving Medication Adherence for Patients with Low Functional Health Literacy:

描述(由申请人提供)：一项关于会说话的药瓶的试点研究简介：在整个医疗保健过程中，功能性健康素养较低的患者可能会因为难以遵循处方的药物治疗方案而导致更差的结果。虽然不遵守的原因可以从个人内部、人际和系统角度得出，但一个起点是患者难以阅读和理解处方瓶标签上的药物说明。标签可以为患者和医疗保健代理人提供重要的提醒和决策支持。然而，必须有阅读和理解标签的技能。我们将使用“会说话的药瓶”来记录处方用药说明，这样患者就可以在家里根据需要重新播放说明。目的：本研究项目的目的是比较在功能健康素养较低且在零售药店购买治疗高血压药物的患者中使用“会说话的药瓶”与常规护理在以下方面的差异：A.操作的可行性，B.设备的实用性，C.服药依从性，D.药物自我管理的自我效能，以及E.血压控制。设计：这一新的干预措施将在太平洋西北部的一家零售药店进行测试。试点试验将采用随机试验设计，有两个研究部门。分析：组内自我效能测量和血压的变化分数将通过配对t检验进行检查；组间测量也将在两个治疗组之间进行检查。我们还将跟踪药物复杂性作为潜在的混杂因素，并进行半结构化的离职面谈。结论：研究结果将有助于确定向零售药店功能健康素养较低的患者提供这项技术的可行性和实用性。在未来的多点随机对照试验中，我们将收集初步的描述性数据以及方差和效应大小测量，以进行疗效评估。公共卫生相关性：功能性健康素养低的患者往往由于难以坚持处方药物治疗方案而导致较差的结果。我们将使用“会说话的药瓶”(即具有可重录音频容量的药物容器)来记录处方用药说明，以便患者可以在家里根据需要重新播放说明。

DESCRIPTION (provided by applicant): A Pilot Study with Talking Pill Bottles Introduction: Across the healthcare continuum, patients with low functional health literacy may have worse outcomes due to difficulties in following prescribed medication regimens. While reasons for non-adherence can be drawn from the intra-personal, interpersonal, and systemic perspectives; one starting point is the difficulty that patients have reading and understanding medication instructions on a prescription bottle labels. Labels can provide a vital reminder and decision support aid for patients and healthcare proxies. Yet, skills must be available for reading and understanding the labels. We will utilize "Talking Pill Bottles" to record prescription medication instructions so that patients can re-play the instructions as needed in their homes. Purpose: The aim of this research project is to compare the use of "Talking Pill Bottles" to usual care in patients who have low functional health literacy and who purchase medications for primary hypertension at a retail pharmacy with regard to: a. feasibility of the procedures, b. utility of the equipment, c. medication adherence, d. self efficacy in medication self management, and e. blood pressure control. Design: This novel intervention will be tested within the context of a retail pharmacy in the Pacific Northwest. The pilot test will use a randomized trial design with two research arms. Analysis: Within-group change scores on a self efficacy measure and blood pressures will be examined with the paired t-test; between group measures will also be examined between the two treatment arms. We will also track medication complexity as a potential confounder and conduct semi- structured exit interviews. Conclusion: Results will help establish the feasibility and utility of providing this technology to patients who have low functional health literacy in a retail pharmacy. We will gather preliminary descriptive data along with variance and effect size measures for power estimations in a future multi-site, randomized controlled trial. PUBLIC HEALTH RELEVANCE: Patients with low functional health literacy often have worse outcomes due to difficulties in adhering to prescribed medication regimens. We will utilize "Talking Pill Bottles" (i.e., medication containers with re-recordable audio capacity) to record prescription medication instructions so that patients can re-play the instructions as needed in their homes.