The Chemistry-Biology Interface Program at Johns Hopkins University

描述（由申请人提供）：本提案寻求对约翰霍普金斯大学化学生物学接口（CBI）培训计划的支持。其目标是培养博士前学生使用化学和生物学的工具进行生物医学研究。该计划是在生物化学和分子生物学（公共卫生的彭博学校）和药理学和分子科学（医学院）的部门教师之间的合作努力，与他们的同事在生物学和化学部门（艺术与科学的Zanvyl Krieger学校）。学生参与者将有一个多样化的研究项目，包括合成，机制，酶学，分子成像和生物大分子结构，从26个研究小组中选择。学生将接受生物和化学科学的课程培训，包括专门为该计划设计的化学生物学两个学期的课程，但对所有约翰霍普金斯大学的学生开放。CBI计划的其他方面包括CBI论坛，学生将在那里举办文学研讨会，捍卫原创研究提案，捍卫他们的论文，以及年度务虚会。CBI计划于2005年秋季启动，使用大学的资金，将于2006年秋季由6名学生组成。要求支持支持4名研究生，增加到6名学生在第三年，随着该方案的势头增加。一个广泛的支持网络，以咨询和指导的形式，以最大限度地提高学生的成功。相关性：化学和生物学在基础和应用生物医学研究中的作用至关重要。现在对能够横跨这两个科学领域的科学家的需求正在迅速增加。约翰霍普金斯大学的CBI项目将培养具有这种能力的科学家。

DESCRIPTION (provided by applicant): This proposal seeks support for a training program at the Chemistry-Biology Interface (CBI) at Johns Hopkins University. The goal is to train predoctoral students to carry out biomedical research using the tools of Chemistry and Biology. The Program is a collaborative effort between faculty in the Departments of Biochemistry and Molecular Biology (Bloomberg School of Public Health) and Pharmacology and Molecular Sciences (School of Medicine), with their colleagues in the Biology and Chemistry Departments (Zanvyl Krieger School of Arts & Sciences). Student participants will have a diverse array of research projects including synthesis, mechanism, enzymology, molecular imaging, and biomacromolecular structure to choose from in 26 research groups. The students will receive coursework training in the biological and chemical sciences, including a two-semester course in Chemical Biology designed especially for the Program, but open to all Johns Hopkins University students. Other aspects of the CBI Program include CBI Forum where students will present literature seminars, defend original research proposals, and defend their theses, as well as an Annual Retreat. The CBI Program was initiated in fall 2005 using funding from the University and will consist of 6 students in fall 2006. Support is requested to support 4 graduate students, increasing to 6 students in year 3, as the momentum of the Program increases. An extensive network of support in the form of advising and mentoring is in place to maximize the students' success. Relevance: The roles of chemistry and biology in basic and applied biomedical research are of paramount importance. There is a rapidly increasing need for scientists who can traverse both fields of science. The CBI Program at Johns Hopkins University will train scientists with this ability.