Training in Endocrine, Metabolic, and Prenatal Basis of Chronic Kidney Disease

描述（由申请人提供）： 这是一个在慢性肾脏疾病的内分泌，代谢和围产期基础培训计划的修订申请，以支持3名博士前学员。总体目标是培养出具有强大翻译方法的高质量独立研究人员，他们可以开发和维持优秀的研究项目。培训教师由来自医学，药学和兽医学院6个系的23名导师组成。该学院由基础科学家和临床科学家组成，他们具有广泛的兴趣和专业知识，其中大部分专注于内分泌-心肾相互作用。博士前学员将通过医学学院的生物医学科学跨学科项目（IDP）进行招募和培训。在过去的3年里，来自整个美国的符合培训补助金条件的候选人平均每年有170人，其中每年约有50人进入培训计划。这些学员进入平均综合口头加定量GRE成绩约1200-1250，本科GPA约3.5。IDP提供全面的讲座和实验室课程，以及实验室轮换和专业学科的高级课程。随后的培训侧重于在选择的实验室进行独立研究，以及在发展沟通技能和研究伦理方面的补充培训。该培训计划的核心课程已经设计，旨在为学生提供适合研究慢性肾脏疾病的内分泌，代谢和产前基础的研究人员的知识。博士前培训通常需要5年左右的时间，第一年由各自的学院提供，平均3-4年的培训补助金和导师研究赠款提供的额外资金预计支持。

DESCRIPTION (provided by applicant): This is a revised application for a training program in Endocrine, Metabolic, and Perinatal Basis of Chronic Kidney Disease to support 3 predoctoral trainees. The overall goal is to produce top quality independent investigators with a strong translational approach who can develop and sustain outstanding research programs. The training faculty consists of 23 mentors from 6 departments in the Colleges of Medicine, Pharmacy, and Veterinary Medicine. The faculty consists of basic scientists and clinician-scientists with a wide range of interests and expertise, much of which is focused on endocrine-cardiorenal interactions. The predoctoral trainees will be recruited and trained through the College of Medicine's Interdisciplinary Program in Biomedical Sciences (IDP). The pool of trainee grant eligible candidates from the entire US has averaged 170/year during the past 3 years with ~ 50/year entering the training program. These trainees enter with an average combined verbal plus quantitative GRE scores of ~1200-1250, and undergraduate GPAs of ~3.5. The IDP provides comprehensive lecture and laboratory courses as well as laboratory rotations and advanced course work in specialized disciplines. Subsequent training focuses on independent research in the laboratory of choice as well as supplemental training in development of communication skills and ethical aspects of research. A core curriculum for this training program has been designed with the intent of providing the students with the knowledge appropriate for researchers working on the endocrine, metabolic, and prenatal basis of chronic kidney disease. The predoctoral training usually takes ~ 5 years with the first year provided by the respective college, an average of 3-4 years support anticipated from the training grant and additional funds supplied by the mentors research grants.