Integrative Training in Biomedical Systems

描述（由申请人提供）：这是一个广泛修订的资助申请，用于培训计划，以支持3名学生在前2年的综合生物医学科学研究生课程（IBGP）的主题为“人类疾病的生物学。“该计划的学生将根据学术成就和对人类疾病机制跨学科研究的兴趣，从IBGP第一年的学生中选出。 在这2年里，学生需要一个严格的，基础广泛的核心课程，包括讲座，研讨会，小组讨论和实验室轮换。 在第一年结束时，所有学生选择论文顾问和咨询委员会，指导他们进行跨学科研究项目，并就高级课程和研讨会的选择向他们提供建议。这些将帮助他们整合与他们的跨学科论文研究有关的材料，这些研究涉及人类疾病机制的复杂相互作用。 第一年后，该计划的学生将参加每年至少一个季度的综合生物医学科学高级研讨会。 为了帮助学生在核心课程完成后选择课程和研讨会，我们设计了9个传统研究学科的建议课程，如果遵循这些课程，将导致他们的最终成绩单将该领域指定为研究生专业。 许多学生在这个程序可能会希望获得研究生专业化在一个以上的领域（称为研究重点领域）。该培训计划在这9个研究重点领域中的每一个领域都有优秀的研究生教师，他们可以担任论文顾问和咨询委员会成员，其中一名教师担任某个领域的教师联络员。 这位教师可以与学生讨论他所代表的研究重点领域的不同方面。候选人资格考试将在第三年年初进行。它将包括：（1）由学生撰写的关于拟议的跨学科论文研究项目的资助申请;（2）口试，以测试学生对拟议的跨学科研究项目相关的信息和概念的整合。 在此之后，大部分学生的努力将花费在研究上，最终将在口头答辩的论文中达到高潮;毕业时间不应超过5年。 我们相信，课程，教师和资源支持这个培训计划将吸引优秀的学生谁将成为杰出的，生产力的科学家在综合生物医学研究。

DESCRIPTION (provided by applicant): This is an extensively revised grant application for a training program to support 3 students in each of the first 2 years of an Integrated Biomedical Science Graduate Program (IBGP) having the theme "The Biology of Human Disease." Students for this program will be selected from the pool of students in the first year of the IBGP on the basis of academic achievements and an interest in interdisciplinary studies on mechanisms of human disease. During these 2 years students take a rigorous, broadly based core curriculum consisting of lectures, seminars, group discussions and laboratory rotations. At the end of year 1 all students choose a dissertation advisor and advisory committee who guide them in an interdisciplinary research project, and advise them on the selection of advanced courses and seminars. These will help them to integrate material related to their cross-disciplinary dissertation research on complex interactions underlying the mechanisms responsible for human disease(s). After the first year, students in the program will take an advanced seminar in integrated biomedical science for at least one quarter each year. To assist students in the choice of courses and seminars after completion of the core courses, we have designed suggested curricula in 9 traditional research disciplines, which if followed will result in their final transcripts designating this area as a graduate specialization. Many students in this program will probably want to obtain graduate specialization in more than one area (referred to as areas of research emphasis). This training program has excellent graduate faculty in each of these 9 areas of research emphasis who can serve as dissertation advisors and advisory committee members, and one of these faculty members serves as a faculty liaison for an area. This faculty member is available to discuss with students different aspects of the area of research emphasis he represents. The candidacy exam will be taken early in the third year. It will consist of: (1) A grant application written by the student on the proposed interdisciplinary dissertation research project; (2) An oral examination to test the student's integration of information and concepts related to the proposed cross-disciplinary research project. Subsequent to this most of the students' efforts will be spent on research that will culminate in a dissertation that will be defended orally; the time to graduation should be no more than 5 years. We believe that the curriculum, faculty and resources supporting this training program will attract outstanding students who will become distinguished, productive scientists in integrative biomedical research.