Multidisciplinary Training Program in Human Imaging
Multidisciplinary Training Program in Human Imaging
批准号:
7448646
负责人:
GEOFFREY DAVID CLARKE
金额:
$25.07万
依托单位国家:
美国
项目类别:
财政年份:
2004
资助国家:
美国
项目状态:
已结题
起止时间:
2004-09-01 至 2010-08-31
中文摘要
这项提议的目标是开发一个多学科人体成像(MDHI)研究培训计划,整合医生、成像科学家和医学物理学家团队的研究活动,这些团队致力于基础科学和以患者为导向的临床调查,以满足以西班牙裔为主的南得克萨斯州社区的特殊健康需求。我们实现这一目标有三个具体目标:(1)为在人类和/或人类疾病动物模型的生物医学成像方面接受培训的医生和成像科学家制定严格的招聘和指导计划;(2)通过扩展新的常驻医学博士/博士(R-MD/PHD)人类成像方面的新轨道,扩大和加强ODR放射科学研究生计划的成功,将弗雷德里克·C·巴特综合临床研究中心(GCRC)研究成像核心产生的临床研究纳入其中;以及(3)增加不同种族的学生的数量,特别是墨西哥裔美国人和其他西班牙裔群体,接受人类行为方面的培训
影像研究。该计划的一个显著特点是在同一学术课程中直接整合了博士研究生研究教育和临床住院医师培训。来自多个医学院部门的常驻医学博士/博士学生参加了已有的医学物理和辐射生物学研究生课程。MDHI学生由一个由知名研究人员组成的网络(其中许多人得到了NIH的资助)通过五个人类成像研究导师核心的合作进行指导。我的研究核心提供了基础设施,弥合了基础科学研究、转化研究和患者临床护理之间的鸿沟。候选人遴选和咨询委员会(CSAC)由来自医学、研究生和牙科学校的15名高级研究人员组成,他们对应用生物医学成像研究方法有着浓厚的兴趣。CSAC挑选MDHI获得者,并评估学生和他们的初级教师导师的表现。由MDHI计划支持的受训人员将成为设计和实施生物医学成像研究的专家,涉及研究人员和人类受试者之间的直接互动。MDHI计划通过促进一个整合和协调的研究和研究培训计划来促进生物医学成像的基础发现,该计划可应用于广泛的生物过程、疾病和疾病以及跨器官系统。
英文摘要
The goal of this proposal is to develop a Multidisciplinary Human Imaging (MDHI) research training program that integrates the investigational activities of physician, imaging scientist and medical physicist teams working on basic science and patient oriented clinical investigations of the exceptional health needs of the predominantly Hispanic South Texas community. We accomplish this goal with three specific aims: (1) develop a rigorous recruiting and mentoring program for physicians and imaging scientists training in biomedical imaging of humans and/or animal models of human disease, (2) expand and build on the success of odr graduate program in Radiological Sciences by extension of the new Resident MD/PhD (R-MD/PhD) track in Human Imaging to include clinical studies arising from the Research Imaging Core of the Frederic C. Bartter General Clinical Research Center (GCRC) and (3) increase the numbers of ethnically diverse students, particularly Mexican-Americans and other Hispanic groups, trained in the conduct of human
imaging research. A distinguishing feature of the program is direct integration of Ph.D. graduate research education and clinical resident training in the same academic curriculum. Resident MD/PhD students from multiple medical school departments join the pre-existing graduate program for medical physics and radiation biology. MDHI students are mentored by a network of established investigators (many with NIH funding) through collaborations fostered by five Human Imaging Research Mentorship Cores. The research cores i provide infrastructure that bridges the gulfs between basic science research, translational research and patient clinical care. The Candidate Selection and Advisory Committee (CSAC) consists of 15 senior investigators from the Medical, Graduate and Dental Schools with strong interest in applying biomedical imaging research methods. The CSAC selects MDHI recipients and evaluates the performance of both the students and their junior faculty mentors. Trainees supported by the MDHI Program will be expert in the design and conduct of biomedical imaging research involving direct interactions between investigators and human subjects. The MDHI Program promotes fundamental discoveries in biomedical imaging by fostering an integrated and coordinated program of research and research training that can be applied to a broad spectrum of biological processes, disorders and diseases and across organ systems.
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DOI:
10.1016/j.ijrobp.2009.11.012
发表时间:
2011-02-01
期刊:
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
影响因子:
7
作者:
[Fuller, Clifton D., Nijkamp, Jasper, Duppen, Joop C., Rasch, Coen R. N., Thomas, Charles R., Jr., Wang, Samuel J., Okunieff, Paul, Jones, William E., III, Baseman, Daniel, Patel, Shilpen, Demandante, Carlo G. N., Harris, Anna M., Smith, Benjamin D., Katz, Alan W., McGann, Camille, Harper, Jennifer L., Chang, Daniel T., Smalley, Stephen, Marshall, David T., Goodman, Karyn A., Papanikolaou, Niko, Kachnic, Lisa A.]
通讯作者:
Kachnic, Lisa A.
Imaging of 186Re-liposome therapy in ovarian cancer xenograft model of peritoneal carcinomatosis.
186Re-脂质体治疗腹膜癌病卵巢癌异种移植模型的成像。
DOI:
10.1080/10611860802230372
发表时间:
2008
期刊:
Journal of drug targeting
影响因子:
4.5
作者:
[Zavaleta,CristinaL, Goins,BethA, Bao,Ande, McManus,LindaM, McMahan,CAlex, Phillips,WilliamT]
通讯作者:
Phillips,WilliamT
Use of avidin/biotin-liposome system for enhanced peritoneal drug delivery in an ovarian cancer model.
使用抗生物素蛋白/生物素-脂质体系统增强卵巢癌模型中的腹膜药物递送。
DOI:
10.1016/j.ijpharm.2007.01.010
发表时间:
2007
期刊:
International journal of pharmaceutics
影响因子:
5.8
作者:
[Zavaleta,CristinaL, Phillips,WilliamT, Soundararajan,Anuradha, Goins,BethA]
通讯作者:
Goins,BethA
Effect of body mass index on shifts in ultrasound-based image-guided intensity-modulated radiation therapy for abdominal malignancies.
体重指数对腹部恶性肿瘤超声图像引导调强放射治疗变化的影响。
DOI:
10.1016/j.radonc.2008.08.002
发表时间:
2009
期刊:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
影响因子:
--
作者:
[Choi,Mehee, Fuller,CliftonD, Wang,SamuelJ, Siddiqi,Ather, Wong,Adrian, ThomasJr,CharlesR, Fuss,Martin]
通讯作者:
Fuss,Martin
Multimodality therapy for locoregional extrahepatic cholangiocarcinoma: a population-based analysis.
DOI:
10.1002/cncr.24572
发表时间:
2009-11-15
期刊:
CANCER
影响因子:
6.2
作者:
[Fuller, Clifton D., Wang, Samuel J., Choi, Mehee, Czito, Brian G., Cornell, John, Welzel, Tania M., McGlynn, Katherine A., Luh, Join Y., Thomas, Charles R., Jr.]
通讯作者:
Thomas, Charles R., Jr.
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Project 2: Developmental Programming & Aging Interactions in Primate CV Function
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项目类别:
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资助金额:$20.63万
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财政年份:2018
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负责人:GEOFFREY DAVID CLARKE
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负责人:GEOFFREY DAVID CLARKE
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Womb to Tomb: Developmental Programming and Aging Interactions in Primates
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负责人:GEOFFREY DAVID CLARKE
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Womb to Tomb: Developmental Programming and Aging Interactions in Primates
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负责人:GEOFFREY DAVID CLARKE
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CORE D: Magnetic Resonance Imaging Core (MRIC)
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资助金额:$12.65万
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财政年份:2018
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负责人:GEOFFREY DAVID CLARKE
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依托单位:
CORE E: Samples and Data Management Core
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批准号:10201486
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项目类别:
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资助金额:$13.5万
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财政年份:2018
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负责人:GEOFFREY DAVID CLARKE
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依托单位:
Project 2: Developmental Programming & Aging Interactions in Primate CV Function
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批准号:10201488
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项目类别:
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资助金额:$20.63万
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财政年份:2018
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负责人:GEOFFREY DAVID CLARKE
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Womb to Tomb: Developmental Programming and Aging Interactions in Primates
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项目类别:
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资助金额:$264.43万
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Imaging Biomarkers for Evaluating Mitochondrial Function in Diabetes
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项目类别:
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资助金额:$15.42万
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财政年份:2011
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负责人:GEOFFREY DAVID CLARKE
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依托单位:
Imaging Biomarkers for Evaluating Mitochondrial Function in Diabetes
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批准号:8325696
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项目类别:
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资助金额:$15.87万
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财政年份:2011
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负责人:GEOFFREY DAVID CLARKE
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Project 2: Developmental Programming & Aging Interactions in Primate CV Function
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财政年份:--
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负责人:GEOFFREY DAVID CLARKE
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Raw-Image微小物体高精度位姿测量法
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