SCORE Program at New Mexico State University, Las Cruces

这是一份申请新墨西哥州州立大学(NMSU)继续计分项目的申请表 克鲁斯。国立密歇根州立大学的一个目标是扩大该机构的研究，以供少数民族学生参与。 希望从事生物医学学科的人。拟议的SCORE计划有其 目标：(1)在今后四年内过渡，74%的经常成绩次级项目调查员将在 这项申请申请了来自NIH的R01资金竞争。(Ii)在未来四年内加强 正在进行第二轮供资的SCORE次级项目所有调查员的出版记录 每年在同行评议、推荐的期刊上发表的研究论文至少多33%。(三)显著 通过开发核心提高NMSU进行生物医学相关研究的能力 研究设施。(四)提高NMSU自我评价、评估和监测成绩的能力 用于机构自学、计划审查、支持更多计划任务的计划，以及 研究管理的内部改进。 本申请包含19个研究子项目和3个试点项目的研究建议。 子项目。这些提案中代表的学科包括农学、动物科学、 生物化学、生物学、化学、分子生物学、微生物学和心理学。的研究课题 建议的项目包括：动物细胞有丝分裂和胞质分裂，内耳感觉器官发生 生长激素轴和瘦素的基因组相互作用，共生弧菌的致病性， 电鱼肌源性细胞中的转录因子，丙型肝炎病毒的翻译控制，适应 鸽子和大鼠对缺氧、传播病原体、微小隐孢子虫、杀菌剂耐受性的研究 金黄色葡萄球菌，谷氨酰胺合成酶的调节，RNAi研究细胞程序性死亡，电子 和生物大分子的机械性能，生物医学应用的金属离子螯合剂，高价 铁络合物作为非血红素铁蛋白的模型，放射性药物的化学合成， 次生代谢、有机合成新杂环和芳香族化合物的转录调控 化合物，植物耐旱性和耐盐性的转录图谱，对映体的选择性结合 通过粘土，以及通过皮质醇和行为同步性来衡量婴儿的学习。这项计分计划将 继续一个29年的MBRS计划，该计划为351名少数民族学生(-81%的理科毕业生)提供了进修机会 参与者)参加毕业后培训，自1974年以来，共获得72个博士学位。

This is an application for a continuing SCORE Program at New Mexico State University (NMSU), Las Cruces. A goal of NMSU is to expand research at the institution for participation by ethnic minority students who desire to pursue careers in the biomedical science disciplines. The proposed SCORE Program has as its goals: (i) To transition, within the next four years, 74% of the investigators of regular SCORE subprojects in this application to competition for R01 funding from NIH. (ii) To enhance within the next four years, the publication records of all investigators of SCORE subprojects, who are in their second cycle of funding, to a minimum of 33% more research manuscripts per year in peer-reviewed, refereed journals. (iii) To significantly improve the capabilities of NMSU to conduct biomedically-relevant research through development of core research facilities. (iv) To improve the capacity of NMSU to self-evaluate, assess, and monitor the SCORE Program for the purpose of institutional self-study, program review, support of MORE Program missions, and internal improvement of research management. This application contains research proposals for nineteen research subprojects and three pilot subprojects. Disciplines represented among these proposals include Agronomy, Animal Science, Biochemistry, Biology, Chemistry, Molecular Biology, Microbiology and Psychology. The research topics of proposed projects include: mitosis and cytokinesis in animal cells, sensory organogenesis during inner ear development, genomic interactions of the growth hormone axis and leptin, pathogenicity in symbiotic vibrios, transcription factors in myogenic cells of electric fish, translational control of hepatitis C virus, adaptations of pigeons and rats to hypoxia, transmission of the pathogen,Cryptosporidium parvum, bacteriocide tolerance of Staphylococcus aureus, regulation of glutamine synthetase, programmed cell death studied by RNAi, electric and mechanical properties of bio-macromolecules, metal ion chelators for biomedical applications, highvalence iron complexes as models for non-heme iron proteins, chemical synthesis of radiopharmaceuticals, transcription regulation of secondary metabolism, organic synthesis of novel heterocyclic and aromatic compounds, transcriptional profiling of drought and salt tolerance in plants, selective binding of enantiomers by clays, and infant learning gauged by cortisol and behavioral synchrony. This SCORE Program will continue a 29-year MBRS Program which has advanced 351 minority students (-81% of B.S.-graduated participants) to post-baccalaureate training, 72 eaming Ph.D. degrees, since 1974.