HIV Prevention in the Family Drug Court

描述（由申请人提供）：该指导患者导向研究职业发展奖（K23）将使临床心理学家候选人成为青少年风险行为领域的独立研究人员，重点关注家庭过程，情绪调节，青少年药物滥用和艾滋病毒风险。该培训奖的总体目标是让候选人将研究成果应用于开发有效的艾滋病毒预防和对滥用药物的少年犯进行药物滥用干预。与没有犯罪的同龄人相比，少年犯在精神病理和情绪困扰方面的发病率更高，因此滥用药物和艾滋病毒风险行为的风险更高。较高的药物使用率和精神病理学大大增加了罪犯感染艾滋病毒的风险。虽然，以家庭为基础的治疗在改变药物使用方面已经证明了一些功效，但它们未能针对青少年的性风险行为，也没有关注一种结构（情绪调节），而这种结构可能是整个家庭长期行为改变的核心。因此，奖励期的研究目标是将目前仅针对青少年的药物滥用少年犯艾滋病毒预防干预影响管理调整（并测试）为有效的基于家庭的药物滥用少年犯艾滋病毒预防干预影响管理。这项研究将分为三个阶段。在第一阶段，将通过焦点小组和适应干预的试点运行，从45对青少年父母夫妇中收集定性数据。在第二阶段，60对夫妇将被随机分配到以家庭为基础的艾滋病毒影响预防组或一般健康促进组，并进行基线和3个月的随访评估。为了估计以家庭为基础的干预的效果大小，将检查每种情况下受试者之间干预反应的差异（例如，青少年物质使用和性风险的变化）。第三阶段将涉及项目总结和数据分析。候选人将通过5年的严格培训和强有力的指导来实现上述所有目标：1)开展临床试验，2)治疗青少年药物滥用，3)发展以家庭为基础的干预措施，解决家庭情绪失调，4)在青少年司法系统内工作。今后针对艾滋病毒感染风险很大的青少年人群的治疗开发工作将根据该项目的结果提供信息。

DESCRIPTION (provided by applicant): This Mentored Patient-Oriented Research Career Development Award (K23) will enable the candidate, a clinical psychologist, to become an independent researcher in the area of adolescent risk behaviors, with a focus on family processes, emotion regulation, adolescent substance abuse and HIV risk. The overarching goal of this training award is for the candidate to apply research findings to the development of efficacious HIV prevention and substance abuse interventions for substance abusing juvenile offenders. Juvenile offenders are at elevated risk for substance abuse and HIV risk behaviors secondary to higher rates of psychopathology and emotional distress than their non-offending peers. Higher rates of substance use and psychopathology substantially increase offenders' risk for HIV infection. Although, family-based treatments have demonstrated some efficacy in changing substance use, they have failed to target adolescent sexual risk behavior and have not focused on a construct (emotion regulation) that may be central to long-term behavior change for the entire family. Thus, the research goal for the Award period is to adapt (and test) a current adolescent-only Affect Management HIV Prevention Intervention for Substance-Abusing Juvenile Offenders into an effective Family-Based Affect Management for HIV Prevention Intervention for Substance- Abusing Juvenile Offenders. This study will have three phases. In Phase 1, qualitative data will be collected from 45 adolescent-parent dyads via focus groups and pilot run-throughs of the adapted intervention. In Phase 2, 60 dyads will be randomized to either the Family-Based Affect HIV prevention or General Health Promotion condition with baseline and 3 month follow-up assessments. Differences in intervention response (e.g., changes in adolescent substance use and sexual risk) between subjects in each condition will be examined in order to estimate the effect size of the Family-Based intervention. Phase 3 will involve project summation and data analysis. The candidate will achieve all of the above with five years of rigorous training and strong mentorship in 1) developing clinical trials, 2) treating adolescent substance abuse, 3) developing family-based interventions that address family emotion dysregulation, and 4) working within the juvenile justice system. Future treatment development work for an adolescent population at great risk for HIV infection will be informed by the results of this project.