Increasing Adherence to Tobacco Cessation Intervention

不坚持使用戒烟药物是非常常见的，而且与戒烟失败高度相关 抽烟。然而，关于如何影响依从性，或者是否更大的依从性，目前知之甚少 实际上会提高戒烟成功率(即，其因果作用尚不清楚)。项目3旨在解决 三个主要目标：(1)找出影响戒烟药物依从性的因素；(2) 确定服药依从性和戒烟之间的联系，以及(3)开发新的， 符合成本效益的依从性干预措施，可在现实世界的医疗保健环境中使用，并且 改善服药依从性和戒烟效果。这些研究目标将是 通过在现实世界的初级保健环境中进行的两个实验来解决，这些实验将评估几种类型 旨在提高依从率和戒烟成功率的承诺遵守干预措施。这些 干预措施包括一种旨在纠正吸烟者对药物的错误信念的认知干预 以及戒烟、提供反馈和基于实时的问题解决咨询的干预 记录用药情况，以及加强依从性的应急管理干预 行为。这项研究的优势在于它将：使用在初级保健环境中招募的吸烟者；揭示 这些坚持干预措施的相对、相加和交互影响；使用多个汇聚的 实现对遵守情况的准确评估的措施；并使用调解分析来揭示 依从性的改变在多大程度上会转化为更高的禁酒率。最后，这项研究将确定 在真实环境中使用的一组最佳遵从性干预措施。这种干预措施可能被用来 广泛的健康状况，其中服药依从性是一个问题。 相关性(请参阅说明)： 大多数吸烟者在戒烟期间没有正确使用戒烟药物，这会减少 成功戒烟的机会。这项拟议的研究将测试旨在增加 吸烟者正确使用戒烟药物，并将测试这是否会提高戒烟成功率。 这项研究有可能改善戒烟治疗，从而改善吸烟者的健康。

Nonadherent use of smoking cessation medications is very common and highly associated with failure to quit smoking. However, little is presently known about how to affect adherence, or whether greater adherence will actually improve cessation success (i.e., its causal role is unknown). Project 3 is designed to address three chief aims: (1) to identify the factors that influence adherence to smoking cessation medication; (2) to determine the association between medication adherence and smoking cessation, and (3) to develop new, cost-effective adherence interventions that are feasible for use in real-world healthcare settings and that improve both medication adherence and smoking cessation outcomes. These research goals will be addressed via two experiments conducted in real-world primary care settings that will assess several types of promising adherence interventions designed to boost both adherence rates and cessation success. These interventions include a cognitive intervention designed to modify smokers' incorrect beliefs about medication and cessation, interventions that provide feedback and problem solving counseling based upon real-time recording of medication use, and a contingency management intervention that reinforces adherence behavior. Strengths of this research are that it will: use smokers recruited in primary care settings; reveal the relative, additive, and interactive effects of these adherence interventions; use multiple, convergent measures to achieve an accurate assessment of adherence; and use mediational analyses to reveal the extent to which adherence change translates into higher abstinence rates. Finally, this research will identify an optimal set of adherence interventions for use in real-world settings. Such interventions might be used for a broad range of health conditions where medication adherence is a problem. RELEVANCE (See instructions): The majority of smokers do not use cessation medications properly during a quit attempt and this decreases the chances of successful quitting. The proposed research will test interventions designed to increase smokers' proper use of cessation medication and will test whether or not this improves cessation success. This research has the potential to improve cessation treatment, and as a result, the health of smokers.