Maternal depression and child weight: Early pathways

描述（由申请人提供）：儿童超重是我们这个时代最重要的健康问题之一，因为它们给个人生活和整个社会带来了负担。母亲抑郁症可能对儿童时期的超重有重大影响。本应用旨在研究母亲抑郁与儿童时期体重变化之间的关系，并系统地探讨解释这种关系的可能机制。我们建议对脆弱家庭（FF）研究和幼儿纵向研究-幼儿园（ECLS-K）进行二次数据分析，这两项研究收集了全国儿童样本中关于母亲抑郁和儿童超重的纵向信息。在FF研究中，信息从出生到三岁（三波）（估计N= 2355），在ECLS-K中，从学前班到五年级（5波）（估计N=8,818）。在FF研究中，使用DSM-IV重度抑郁症（简称CIDI）筛查来测量母亲抑郁症，而在ECLS-K中，使用广泛使用的抑郁量表（ECD-S）的简要版本来测量。提出的分析的具体目的是检验：(1)在儿童时期不同阶段母亲抑郁和体重之间的关系；（II）社会或种族/民族差异在儿童体重中解释利益关系的作用；（III）具体的预防/治疗相关机制，包括不良的饮食习惯和缺乏体育活动，这些可能解释了兴趣关系。数据将使用纵向多元统计回归分析技术和结构化方程模型进行分析，控制重要的相关性。了解母亲抑郁与儿童超重之间关系的机制，为儿童肥胖的预防和治疗提供了巨大的潜力。鉴于治疗体重问题的有效性有限，阐明这一重要途径将为开发新的预防干预措施提供重要信息。

DESCRIPTION (provided by applicant): Childhood overweight is one of the most important health issues of our times, given their burden to individual lives and society as a whole. It is possible that maternal depression has a significant impact at overweight in childhood. This application aims to examine the relationship between maternal depression and weight change during childhood and systematically investigate possible mechanisms explaining this relationship. We propose to conduct secondary data analysis of the Fragile Families (FF) Study and the Early Childhood Longitudinal Study - Kindergarten (ECLS-K), which collected longitudinal information about maternal depression and overweight in childhood in national samples of children. In the FF study, information is available from birth to three years (three waves) (estimated N=2,355) and in the ECLS-K, from pre-K to 5th grade (5 waves) (estimated N=8,818). Maternal depression was measured, in the FF study, using a screening for DSM-IV major depressive disorder (the CIDI short form), and in the ECLS-K, by a brief version of a widely used depression scale (ECD-S). The specific aims of the proposed analysis are to examine: (I) the relationship between maternal depression and weight during different phases of childhood; (II) the role of social or racial/ethnic disparities in childhood weight in explaining the relationship of interest; and (III) specific prevention/treatment relevant mechanisms, including poor dietary practices and lack of physical activity that may account for the relationship of interest. Data will be analyzed using longitudinal multivariate statistical regression analysis techniques and structured equation modeling, controlling for important correlates. Understanding mechanisms explaining the relationship between maternal depression and overweight in childhood offers great potential to inform prevention and treatment of childhood obesity. Given the limited effectiveness of treatment for weight problems, elucidating this significant pathways will provide important information for developing new preventive interventions.