Developing An Effective Community Ethical Review Model

尽管联邦政策旨在保护参与科学研究的人类受试者， 严重的伦理挑战继续出现在环境健康研究中，这似乎会产生负面影响 有色人种社区和低收入社区的安全和福利。这个问题将得到解决 由一个跨学科的研究团队组成，该团队来自西哈莱姆区现有的合作 环境行动公司(WE ACT)，位于曼哈顿北部的NIEHS环境健康中心， 和哥伦比亚儿童环境健康中心(后两个组织都是 哥伦比亚大学梅尔曼公共卫生学院)将实施一项教育和示范项目， “建立一个有效的社区伦理审查模式。”该项目将教育研究人员 (具体地说，NIEHS资助研究的首席调查人员和联合调查人员)和社区 成员(具体地说，NIEHS-或CDC的社区组织顾问和研究伙伴) 资助的研究和其他致力于环境健康问题的有色人种社区-大多数 关于加强人类主体保护的最佳做法)。这将是公元前 通过开发、实施和评估可复制的模式来确保 对基因-环境和非治疗性环境健康研究进行有效的社区审查。 (具体地说，该项目将侧重于关于糖尿病病因和病情恶化的研究的伦理问题 哮喘[包括遗传因素]和对哮喘和铅的家庭干预。这些研究研究 之所以被选中，是因为项目团队在这些研究方面有广泛的经验，而且因为这些研究 都是全国范围内的利益。)示范模型将基于(1)对社区的评估 成员、研究人员和健康资助者对环境健康危害和研究道德的知识； (2)现有社区伦理审查模式的案例研究；(3)语言和文化上的适宜性 关于环境健康和研究道德的教育材料和培训；(4)地方和国家 关于研究伦理的对话；以及(5)对所有项目活动的评估。

Despite federal policies that are designed to protect human subjects involved in scientific research studies, serious ethical challenges continue to occur in environmental health research that appear to negatively impact the safety and welfare of communities of color and low-income communities. This problem will be addressed by an interdisciplinary research team drawn from an existing collaboration between West Harlem Environmental Action, Inc. (WE ACT), the NIEHS Center For Environmental Health in Northern Manhattan, and the Columbia Center for Children's Environmental Health (the latter organizations are both part of Columbia's Mailman School of Public Health) who will implement an educational and demonstration project, "Developing an Effective Community Ethical Review Model." The project will educate researchers (specifically, Principal Investigators and Co-Investigators of NIEHS-funded studies) and community members (specifically, community-based organization advisors and research partners on NIEHS- or CDC- funded studies and others who are working on environmental health issue sin communities of color- most of whom are women of color) on the best practices for bolstering human subject protection. This will bc accomplished through the development, implementation, and evaluation of a replicable model for ensuring effective community review of gene-environment and non-therapeutic environmental health research. (Specifically, the project will focus on ethical issues regarding research on the etiology and exacerbation of asthma [including genetic factors] and home-based interventions on asthma and lead. These research studies have been chosen because the project team has broad experience with these studies and because such studies are of nationwide interest.) The demonstration model will be based upon (1) an assessment of community members', researchers', and health funders' knowledge of environmental health hazards and research ethics; (2) case studies of existing community ethical review models; (3) linguistically and culturally appropriate educational materials and trainings on environmental health and research ethics; (4) local and national dialogues regarding research ethics; and (5) evaluation of all project activities.