MOLECULAR BIOLOGY-BIOCHEMISTRY MODULE

本单元的职能多年来不断演变， 不断变化的技术以及我们集团不断变化的需求。该模块最初是作为一个 生物化学模块。三个周期前，当分子方法开始广泛使用时， 添加了一个组件，使其成为生物化学-分子生物学模块。现在“分子”的顺序 模块名称中的“生物学”和“生物化学”已被颠倒，以反映分子方法的使用 目前，该模块的主要活动。然而，该模块继续提供生物化学 这是参与教师所需要的资源。 这是我们最常用的模块之一。其主要功能是为以下方面提供共用工具： 分子和生物化学分析，得到很好的维护和访问，并提供熟练的技术 支持执行各种常用协议。还有一个重要的教学组成部分， 模块：模块主任帮助核心参与者开发分子方法来回答他们的问题。 研究问题，模块主管和技术人员一起指导研究人员及其工作人员 实验程序和仪器使用的实际方面。 为配合该模块在人类样本基因分析方面的应用日益广泛，我们计划增设一个 模块工作人员的兼职临床研究协调员。帮助人类受试者研究的机会是 核心咨询委员会确定为我们核心单元中最迫切的新员工需求。与 增加一名临床研究协调员，因此本模块将能够协助研究者起草 人类受试者方案以及招募受试者、获取样本和管理患者的所有方面 记录

The functions of this Module have evolved over the years in response to changing technology and therefore the changing needs of our group. The Module was originally established as a Biochemistry Module. Three cycles ago when molecular methods came into widespread use, a molecular biology component was added making it the Biochemistry-Molecular Biology Module. Now the order of "Molecular Biology" and "Biochemistry" in the Module name has been reversed to reflect that the use of molecular methods is currently the major activity of the Module. The Module does, however, continue to provide the biochemistry resources that are needed by the participating faculty. This is one of our most heavily used Modules. Its major functions are to provide shared-use instruments for molecular and biochemical analyses that are well maintained and accessible, and to provide skilled technical support to perform a variety of commonly used protocols. There is also an important instructional component to the Module: the Module directors help Core participants develop molecular approaches for answering their research questions, and together the Module directors and technician instruct investigators and their staff in the practical aspects of the experimental procedures and instrument use. In response to the expanding use of the Module for genetic analysis of human samples, we plan to add a part time clinical research coordinator to the Module staff. Access to help with human subjects research was identified by the Core Advisory Committee as the most pressing new staffing need in our Core Modules. With the addition of a clinical research coordinator, this Module will therefore be able to assist investigators with drafting human subjects protocols and with all aspects of recruiting subjects, obtaining samples, and managing patient records.