Administrative

主要由Holtzman博士和资深博士)将提供科学和管理 如上所述，SCCOR计划的所有方面的指导。特别是，方向对于保持 SCCOR研究人员之间的沟通，以促进基础科学的互动和快速翻译 对临床研究方案的观察。 PHS 398/2590(09/04版)第411页延续格式页 核心A：Holtzman，Michael J.首席调查员/项目主任(最后、第一、中间)：Holtzman，Michael J. 2.谘询委员会 核心将协调与内部咨询委员会的年度会议，在会议上，SCCOR的进展是 提交并进行了批判性审查。我们选择了一个内部(与外部)委员会，主要有两个原因： (1)地方行政人才(SCCOR成员科室科长 生物学/生理学、遗传学、医学、病理学/免疫学、儿科学、物理学和放射学) 杰出的科学家和免疫学家等非常适合为SCCOR计划提供建议；以及(2)我们 希望在选择外部顾问时保持灵活性，因此考虑成立常设委员会 不如临时顾问那么可取。 3.顾问公司 核心还将协调项目和核心提案中所列外部顾问的访问。如上所述 上面，我们选择使用这种外部咨询机制(而不是外部咨询委员会)来 随着SCCOR研究的进展，允许灵活地选择顾问。 4.预算支持 核心将负责管理所有预算并监测SCCOR的支出 调查人员。每个调查员将收到一份月度报表，详细说明他们项目的财务活动。 用品和设备的订单是使用在线计算机服务下的，这有助于降低成本 会计学。核心还将负责维护记录，以应对内部和外部 对SCCOR活动的审计。 5.人员保障 核心将负责启动与大学人力资源部的所有联系，并 用于处理与就业状况和工作福利相关的问题。 6.稿件准备 该核心将协助编写手稿，并将协调与出版有关的活动 SCCOR数据。此外，核心将负责维护一个以计算机为基础的参考图书馆 用于与SCCOR项目相关的手稿准备和搜索。 7.进度报告和其他函件 该核心将负责协助编写所有进展报告。此外，核心人员将 准备和/或促进SCCOR调查人员与其合作者的任何通信。 8.批准人类及动物使用 该核心将维持所有人类和动物用途的批准，并将促进每年更新批准 基础。 9.信息处理 该核心将协助以计算机为基础的文献搜索，并将提供数据设施和人员 演示文稿(包括以计算机为基础的演示文稿和用于高空投影的影印)以及 彩色和黑白复印。出版费用已纳入个别项目的预算。 10.计算机支持和电子通信 该构成部分(主要由Vogelgesang先生提供)将为 SCCOR计划。这一支持的主要目标是为所有SCCOR调查人员保持电子联系 彼此之间以及他们的合作者/同事之间。目前的系统利用本地电子设备的优势 连接到其他部门和其他服务的电子邮件-

primarily by Dr. Holtzman and Dr. Senior) will provide scientific and administrative direction for all aspects of the SCCOR program as noted above. In particular, direction is critical for maintaining communication among SCCOR investigators to facilitate interaction and rapid translation of basic science observations to clinical research protocols. PHS 398/2590 (Rev. 09/04) Page 411 Continuation Format Page Core A: Holtzman, Michael J. Principal Investigator/Program Director (Last, First, Middle): Holtzman, Michael J. 2. Advisory committee The Core will coordinate an annual meeting with the Internal Advisory Committee in which SCCOR progress is presented and critically reviewed. We selected an internal (versus external) committee for two main reasons: (1) the local administrative talent (Department Heads of SCCOR member DepartmentsCell Biology/Physiology, Genetics, Medicine, Pathology/Immunology, Pediatrics, Physics, and Radiology) are also outstanding scientists and immunologists and so are ideally suited to advise the SCCOR program; and (2) we wanted to maintain flexibility in our choice of outside advisors so that a standing committee was considered less desirable than ad hoc consultants. 3. Consultants The Core will also coordinate visits from external consultants listed in the project and core proposals. As noted above, we opted to use this mechanism for external advice (rather than an external advisory committee) to allow for flexibility in consultant selection as SCCOR research progresses. 4. Budget support The core will be responsible for management of all budgets and for monitoring expenditures for SCCOR investigators. Each investigator will receive a monthly statement detailing the financial activity of their project. Orders for supplies and equipment are placed using an on-line computer service that facilitates cost accounting. The core will also be responsible for maintaining records in response to internal and external audits of SCCOR activities. 5. Personnel support The Core will be responsible for initiating all contact with the University department for human resources and for handling issues related to employment status and job benefits. 6. Manuscript preparation The core will provide assistance in preparing manuscripts and will coordinate activities related to publication of SCCOR data. In addition, the Core will be responsible for maintaining a computer-based reference library for use in manuscript preparation and searches relevant to SCCOR projects. 7. Progress reports and other correspondence The core will be responsible for facilitating preparation of all progress reports. In addition, core personnel will prepare and/or facilitate any correspondence of SCCOR investigators with their collaborators. 8. Approval for human and animal use The core will maintain all human and animal use approvals and will facilitate renewal of approvals on an annual basis. 9. Information handling The core will assist in computer-based literature searches and will provide facilities and personnel for data presentation (including computer-based presentations and photocopying for overhead projection) as well as for color and black and white photocopying. Publication costs are incorporated into budgets for individual projects. 10. Computer support and electronic communication This component (provided primarily by Mr. Vogelgesang) will provide all support for computer services for the SCCOR program. A primary goal of this support is to maintain electronic linkage for all SCCOR investigators with each other and with their collaborators/colleagues. The current system takes advantage of local electronic mail interfaced to other Departments and to other services off-