Outcomes and Biostatistics

核心G：结果和生物统计学 核心工作人员将包括核心主任伊拉B威尔逊，塔夫茨大学医学副教授，以及共同 主任约瑟夫霍根，生物统计学副教授在布朗。核心教师包括 Zhijin Wu，生物统计学助理教授（布朗）和John Wong，医学教授，Denise 雅各布森，医学助理教授和英加彼得，流行病学助理教授（都在塔夫茨）， 专业人员包括Fizza Gillani博士（Miriam医院数据库经理和协调员）和 Allison Delong，Brown的生物统计学家和统计程序员。 威尔逊博士和霍根博士共同监督核心的活动，并负责宣传资源， 优先考虑使用核心资源的请求，并管理核心教师和工作人员的日常运作。 核心的基本目的是提供与定量相关的服务、咨询和协作 艾滋病毒研究的LTB CFAR的教师附属机构的方面。核心活动和专业知识范围广泛， 并包括选择和评价成果的措施，建设项目数据库（包括 基于网络的条目），使用各种设计（例如，临床试验，观察性研究）设计和分析研究 研究，实验室实验），并实施成本效益和 决策。核心方案高度重视将导致赠款资助的活动（如写作 建议，协助试点研究，参与手稿撰写），特别强调 与初级调查员合作并指导他们。 核心正在采取的新举措包括扩大我们在生物信息学方面的能力， 基因组分析，在快速发展的神经艾滋病领域开发新的定量专业知识，以及， 利用大量的本地专业知识，促进药物依从性分析领域的发展 数据 核心教职员工与Lifespan/Tufts/Brown的其他核心成员合作 CFAR是资助研究的积极合作者，并密切参与了 初级调查员与CFAR调查人员的合作导致了重要的新研究， 方法论;事实上，协作和方法论研究之间的协同作用是一个定义 这是我们核心的特点和值得注意的力量。

Core G: Outcomes and Biostatistics Staff of the core will include Core Director Ira B Wilson, Associate Professor of Medicine at Tufts, and Co- Director Joseph Hogan, Associate Professor of Biostatistics at Brown. Faculty members of the core include Zhijin Wu, Assistant Professor of Biostatistics (Brown) and John Wong, Professor of Medicine, Denise Jacobsen, Assistant Professor of Medicine and Inga Peter, Assistant Professor of Epidemiology (all at Tufts), Professional staff includes Dr Fizza Gillani (Database Manager and Coordinator at Miriam Hospital) and Ms Allison Delong, Biostatistician and Statistical Programmer at Brown. Drs Wilson and Hogan jointly oversee activities of the core and are responsible for publicizing resources, prioritizing requests for using core resources, and managing day-to-day operations of core faculty and staff. The basic purpose of the core is to provide service, consultation and collaboration related to quantitative aspects of HIV research for faculty affiliates of LTB CFAR. Core activities and expertise are wide ranging, and include selection and evaluation of outcomes measures, construction of project databases (including web-based entry), design and analysis of studies using various designs (e.g^ clinical trial, observational study, laboratory experiments), and implementation of models and methods for cost effectiveness and decision making. The core places high priority on activities that will lead to grant funding (e.g. writing proposals, assisting with pilot studies, participating in manuscript writing), with special emphasis on collaborating with and mentoring junior investigators. New initiatives being undertaken by the core include expanding our capabilities in bioinformatics and genomic analysis, developing new quantitative expertise in the rapidly growing area of neuro-AIDS, and, drawing on considerable local expertise, facilitating growth in the area of analyzing medication adherence data. Core faculty and staff have collaborated with members of every other core in the Lifespan/Tufts/Brown CFAR, are active collaborators on funded research, and have been intimately involved in development of junior investigators. Collaborations with CFAR investigators have led to important new research in methodology; indeed, the synergy between collaborative and methodologic research is a defining characteristic and noteworthy strength of our core.